Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited
Cannabinoids are compounds with pleiotropic properties that act on the cannabinoid receptors, CB1 and CB2, and are divided into endocannabinoids, the endogenous ligands of these receptors, synthetic cannabinoids and phytocannabinoids. The latter are derived from the plant Cannabis sativa. The therap...
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| Format: | Article |
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Wiley
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51035/ |
| _version_ | 1848798397407952896 |
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| author | Constantinescu, Cris S. Gershkovich, Pavel |
| author_facet | Constantinescu, Cris S. Gershkovich, Pavel |
| author_sort | Constantinescu, Cris S. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Cannabinoids are compounds with pleiotropic properties that act on the cannabinoid receptors, CB1 and CB2, and are divided into endocannabinoids, the endogenous ligands of these receptors, synthetic cannabinoids and phytocannabinoids. The latter are derived from the plant Cannabis sativa. The therapeutic and psychoactive properties of this plant have been observed and used for centuries. Of the over 60 compounds that are unique to Cannabis sativa, the substances that have been attributed the greatest therapeutic potential are Δ9‐ tetrahydrocannabinol (THC) and cannabidiol (CBD), both of which, used alone or combined with each other, have become approved drugs. |
| first_indexed | 2025-11-14T20:19:07Z |
| format | Article |
| id | nottingham-51035 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:19:07Z |
| publishDate | 2018 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-510352020-05-04T19:43:23Z https://eprints.nottingham.ac.uk/51035/ Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited Constantinescu, Cris S. Gershkovich, Pavel Cannabinoids are compounds with pleiotropic properties that act on the cannabinoid receptors, CB1 and CB2, and are divided into endocannabinoids, the endogenous ligands of these receptors, synthetic cannabinoids and phytocannabinoids. The latter are derived from the plant Cannabis sativa. The therapeutic and psychoactive properties of this plant have been observed and used for centuries. Of the over 60 compounds that are unique to Cannabis sativa, the substances that have been attributed the greatest therapeutic potential are Δ9‐ tetrahydrocannabinol (THC) and cannabidiol (CBD), both of which, used alone or combined with each other, have become approved drugs. Wiley 2018-07-01 Article PeerReviewed Constantinescu, Cris S. and Gershkovich, Pavel (2018) Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited. European Journal of Neurology, 25 (7). pp. 905-906. ISSN 1351-5101 https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.13658 doi:10.1111/ene.13658 doi:10.1111/ene.13658 |
| spellingShingle | Constantinescu, Cris S. Gershkovich, Pavel Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited |
| title | Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited |
| title_full | Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited |
| title_fullStr | Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited |
| title_full_unstemmed | Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited |
| title_short | Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited |
| title_sort | therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited |
| url | https://eprints.nottingham.ac.uk/51035/ https://eprints.nottingham.ac.uk/51035/ https://eprints.nottingham.ac.uk/51035/ |