IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development

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IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development

Studies in murine cell lines and in mouse models suggest that IL-15 promotes myogenesis and may protect against the inflammation-mediated skeletal muscle atrophy which occurs in sarcopenia and cachexia. The effects of IL-15 on human skeletal muscle growth and development remain largely uncharacteris...

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Bibliographic Details
Main Authors:	O’Leary, Mary F., Wallace, Graham R., Bennett, Andrew J., Tsintzas, Kostas, Jones, Simon W.
Format:	Article
Published:	Nature Publishing Group 2017
Subjects:	Ageing; Muscle stem cells
Online Access:	https://eprints.nottingham.ac.uk/50963/

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