Synthesis and in vitro phototoxicity of multifunctional Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin-coated gold nanoparticles assembled via axial coordination with imidazole ligands

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Synthesis and in vitro phototoxicity of multifunctional Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin-coated gold nanoparticles assembled via axial coordination with imidazole ligands

Hypothesis Metalloporphyrins are extensively investigated for their ability to form reactive oxygen species and as potent photosensitisers for use in photodynamic therapy. However, their hydrophobicity generally causes solubility issues concerning in vivo delivery due to lack of distribution and...

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Bibliographic Details
Main Authors:	Alea-Reyes, Maria E., Penon, Oriol, García Calavia, Paula, Marín, María J., Russell, David A., Pérez-García, Lluïsa
Format:	Article
Published:	Elsevier 2018
Subjects:	Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin; Gold nanoparticles; Imidazole ligands Zn(II)-imidazole axial coordination; Singlet oxygen production; SK-BR-3 cells; Cellular uptake; Dark cytotoxicity; Phototoxiciy; Photodynamic therapy
Online Access:	https://eprints.nottingham.ac.uk/50850/

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