Cordycepin affects growth factor-dependent gene expression
The natural compound cordycepin (3’-deoxyadenosine) causes a reduction in breast cancer cell viability. Microarray analysis showed that growth related genes are down-regulated by cordycepin. Indeed, mTOR, ERK and AMPK signalling was shown to be altered by cordycepin, but the effect was too fast to b...
| Main Author: | Lin, Jialiang |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/50823/ |
Similar Items
A Potential Effect of Cordycepin on the Feedback between Polyadenylation and PI3K/Akt/mTOR Signalling
by: Lawrence, Steven
Published: (2023)
by: Lawrence, Steven
Published: (2023)
The bacteriophage carrier state of Campylobacter jejuni features changes in host non-coding RNAs and the acquisition of new host-derived CRISPR spacer sequences
by: Hooton, Steven P.T., et al.
Published: (2016)
by: Hooton, Steven P.T., et al.
Published: (2016)
The effect of the polyadenylation inhibitor Cordycepin on MCF-7 cells
by: Khurshid, Asma
Published: (2015)
by: Khurshid, Asma
Published: (2015)
Global miRNA expression profiling of domestic cat livers following acute Toxoplasma gondii infection
by: Cong, Wei, et al.
Published: (2017)
by: Cong, Wei, et al.
Published: (2017)
Targeting tumour-astrocyte crosstalk for rational identification of novel therapeutic targets for atypical Teratoid/ Rhabdoid tumours
by: Porter, Harry
Published: (2025)
by: Porter, Harry
Published: (2025)
Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches
by: Onyido, Emenike K., et al.
Published: (2016)
by: Onyido, Emenike K., et al.
Published: (2016)
Cordycepin and the entomopathogenic fungus Cordyceps militaris
by: Wellham, Peter A D
Published: (2022)
by: Wellham, Peter A D
Published: (2022)
Development of cordycepin formulations for preclinical and clinical studies
by: Lee, Jong Bong, et al.
Published: (2017)
by: Lee, Jong Bong, et al.
Published: (2017)
Characterization of miR-3099-mediated posttranscriptional of target genes regulation during neurogenesis in mice
by: Zainal Abidin, Shahidee
Published: (2019)
by: Zainal Abidin, Shahidee
Published: (2019)
RNA-sequencing reveals the complexities of the transcriptional response to lignocellulosic biofuel substrates in Aspergillus niger
by: Archer, David B.
Published: (2014)
by: Archer, David B.
Published: (2014)
Host adaption to the bacteriophage carrier state of Campylobacter jejuni
by: Brathwaite, Kelly J., et al.
Published: (2015)
by: Brathwaite, Kelly J., et al.
Published: (2015)
Transcriptional analysis of Bdellovibrio bacteriovorus responses to different prey and environments
by: Lambert, Carey
Published: (2022)
by: Lambert, Carey
Published: (2022)
Is mitochondrial gene expression coordinated or stochastic?
by: Lee, R.G., et al.
Published: (2018)
by: Lee, R.G., et al.
Published: (2018)
Identifying potential RNA editing sites from RNA-Sequencing data from human brain tissue
by: North, Francesca Louise
Published: (2018)
by: North, Francesca Louise
Published: (2018)
Transcriptional landscape of Aspergillus niger at breaking of conidial dormancy revealed by RNA-sequencing
by: Novodvorska, Michaela, et al.
Published: (2013)
by: Novodvorska, Michaela, et al.
Published: (2013)
Transcriptomic analysis of mouse liver reveals a potential hepato-enteric pathogenic mechanism in acute Toxoplasma gondii infection
by: He, Jun-Jun, et al.
Published: (2016)
by: He, Jun-Jun, et al.
Published: (2016)
The role of Agr quorum sensing on sporulation and solvent formation in Clostridium beijerinckii
by: Boak, Lauren
Published: (2024)
by: Boak, Lauren
Published: (2024)
Optimization Of RNA Extraction And Generation Of Expressed Sequence Tags From Sargassum Binderi (Sonder) J. Agardh
by: Wong, Tony Kok Min
Published: (2005)
by: Wong, Tony Kok Min
Published: (2005)
The role of the CBLL1/HAKAI E3 Ubiquitin Ligase component and its association with the RNA methyltransferase complex in breast cancer
by: Thompson, Rachel
Published: (2025)
by: Thompson, Rachel
Published: (2025)
Characterisation and Intercellular Mechanistic Analysis of Supramolecular, Cationic, mRNA-Loaded Polyplexes for Efficient Transfection in HEK293T and A549 Cells
by: Smith, Silvia
Published: (2023)
by: Smith, Silvia
Published: (2023)
Development of delayed ripening papaya (Carica papaya L.) CV. 'eksotika' using RNA interference and antisense technologies
by: Sekeli, Rogayah
Published: (2013)
by: Sekeli, Rogayah
Published: (2013)
A consensus approach to vertebrate de novo transcriptome assembly from RNA-seq data: assembly of the duck (Anas platyrhynchos) transcriptome
by: Moreton, Joanna, et al.
Published: (2014)
by: Moreton, Joanna, et al.
Published: (2014)
Reference-free assembly of long-read transcriptome sequencing data with RNA-Bloom2
by: Nip, K.M., et al.
Published: (2023)
by: Nip, K.M., et al.
Published: (2023)
Development of a stable T7 RNA polymerase expressing cell line using a lentivirus system
by: Yeong, Ming Yue
Published: (2019)
by: Yeong, Ming Yue
Published: (2019)
Development of miRNA-mimic nanoparticles for the treatment of brain tumours
by: Anithiya Ramamoorthi Gopalram, Shubaash
Published: (2017)
by: Anithiya Ramamoorthi Gopalram, Shubaash
Published: (2017)
The effect of hypoxia and reoxygenation on STAT3 regulation in potential cardiomyocyte models
by: Evans, Emma Louise
Published: (2012)
by: Evans, Emma Louise
Published: (2012)
Transcriptomic responses of mixed cultures of ascomycete fungi to lignocellulose using dual RNA-seq reveal inter-species antagonism and limited beneficial effects on CAZyme expression
by: Daly, Paul, et al.
Published: (2017)
by: Daly, Paul, et al.
Published: (2017)
The molecular impact of physical exercise on a rodent model of schizophrenia: hippocampal gene expression and miRNA levels
by: Bisnauthsing, Hemlata
Published: (2019)
by: Bisnauthsing, Hemlata
Published: (2019)
Identifying wheat root traits and regulatory genes for nitrogen uptake efficiency
by: Griffiths, Marcus
Published: (2018)
by: Griffiths, Marcus
Published: (2018)
Sugar-coated nanoparticles: Investigating lipid-terminated glycopolymers for targeted nanoparticle delivery of nucleic acids
by: Fiedler, Benjamin
Published: (2024)
by: Fiedler, Benjamin
Published: (2024)
An investigation of the expression of pigment genes in Mycobacterium avium subspecies paratuberculosis, strain K10
by: Nguyen Le, Thanh
Published: (2017)
by: Nguyen Le, Thanh
Published: (2017)
Correlation between HPV infection and human beta-defensin mRNA expression in pterygium and normal conjunctiva epithelial cells
by: Aliyu, Abubakar Saadatu
Published: (2017)
by: Aliyu, Abubakar Saadatu
Published: (2017)
Purification of enzyme and influence of substrate specificity on â-1,6-glucanase gene expression in Trichoderma harzianum
by: Mustafa, Muskhazli, et al.
Published: (2009)
by: Mustafa, Muskhazli, et al.
Published: (2009)
Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs
by: Dhir, Ashish, et al.
Published: (2015)
by: Dhir, Ashish, et al.
Published: (2015)
MicroRNA Regulation in the Inflammatory Response
by: Martin, Athena
Published: (2023)
by: Martin, Athena
Published: (2023)
RNAi-mediated gene silencing of lanosterol 14α- demethylase (ERG11)-encoding gene in ganoderma boninense
by: Lim, Fook Hwa
Published: (2022)
by: Lim, Fook Hwa
Published: (2022)
Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency
by: Capel, Victoria, et al.
Published: (2016)
by: Capel, Victoria, et al.
Published: (2016)
RNA interference therapeutics for cancer: challenges and opportunities
by: Bora, R., et al.
Published: (2012)
by: Bora, R., et al.
Published: (2012)
Programming the tomato genome with LED light
by: Grundy, Steven
Published: (2019)
by: Grundy, Steven
Published: (2019)
Mixed anionic and cationic polyphosphazene complexes for effective gene delivery to glioblastoma in vitro and in vivo
by: Hsu, Wei-Hsin
Published: (2018)
by: Hsu, Wei-Hsin
Published: (2018)
Similar Items
-
A Potential Effect of Cordycepin on the Feedback between Polyadenylation and PI3K/Akt/mTOR Signalling
by: Lawrence, Steven
Published: (2023) -
The bacteriophage carrier state of Campylobacter jejuni features changes in host non-coding RNAs and the acquisition of new host-derived CRISPR spacer sequences
by: Hooton, Steven P.T., et al.
Published: (2016) -
The effect of the polyadenylation inhibitor Cordycepin on MCF-7 cells
by: Khurshid, Asma
Published: (2015) -
Global miRNA expression profiling of domestic cat livers following acute Toxoplasma gondii infection
by: Cong, Wei, et al.
Published: (2017) -
Targeting tumour-astrocyte crosstalk for rational identification of novel therapeutic targets for atypical Teratoid/ Rhabdoid tumours
by: Porter, Harry
Published: (2025)