The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis

QR Code

The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis

BACKGROUND: As only a minor portion of the information present in histological sections is accessible by eye, recognition and quantification of complex patterns and relationships among constituents relies on digital image analysis. In this study, our working hypothesis was that, with the application...

Full description

Bibliographic Details
Main Authors:	Roxanis, I., Colling, R., Kartsonaki, C., Green, A.R., Rakha, E.A.
Format:	Article
Published:	BioMed Central 2018
Subjects:	Breast cancer; Digital image analysis; Prognosis; Microarchitecture; Tumour nests
Online Access:	https://eprints.nottingham.ac.uk/50701/

Similar Items

The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours
by: El Ansari, Rokaya, et al.
Published: (2018)

Exploring the role of tumour microenvironment in the behaviour of breast ductal carcinoma in situ
by: Toss, Michael Salah Shawky
Published: (2020)

The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes
by: El Ansari, Rokaya, et al.
Published: (2018)

Deciphering the morphological features underlying breast cancer behaviour using computational pathology and Artificial intelligence (with focus on the role of the tumour microenvironment)
by: Ghannam, Suzan
Published: (2025)

An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation
by: Candido Dos Reis, Francisco J., et al.
Published: (2017)

Serum autoantibodies as tumour markers in breast cancer: their role in screening, diagnosis and prognosis
by: Khan, Hamed N.
Published: (2009)

Rho-GTPase activating protein 18: a biomarker associated with good prognosis in invasive breast cancer
by: Aleskandarany, Mohammed A., et al.
Published: (2017)

The presence of tumour-associated lymphocytes confers a good prognosis in pancreatic ductal adenocarcinoma: an immunohistochemical study of tissue microarrays
by: Tewari, Nilanjana, et al.
Published: (2013)

Phenotypic characterization of breast cancer: the role of CDC42
by: Chrysanthou, Eleni, et al.
Published: (2017)

Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue sections
by: Muftah, Abir A., et al.
Published: (2017)

Clinical and biological roles of Kelch-like family member 7 in breast cancer: a marker of poor prognosis
by: Kurozumi, Sasagu, et al.
Published: (2018)

The identification of targeting peptides and tumour associated antigens for the treatment and early detection of triple negative breast cancer
by: Wilde, Megan
Published: (2023)

MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer
by: Craze, Madeleine L., et al.
Published: (2017)

Amino acid transporters in breast cancer: promising prognostic markers and emerging targets across molecular subtypes
by: El Ansari, Rokaya
Published: (2020)

Heterogeneity of Tumour Infiltrating Lymphocytes (TILs) in breast cancer and its prognostic significance
by: Althobiti, Maryam, et al.
Published: (2018)

Heterogeneity of tumour infiltrating lymphocytes (TILs) in breast cancer and its prognostic significance
by: Althobiti, Maryam, et al.
Published: (2018)

Image segmentation method for boundary detection of breast thermography using random walkers
by: Moghbel, Mehrdad
Published: (2013)

Cancer reversion with oocyte extracts is mediated by cell cycle arrest and induction of tumour dormancy
by: Saad, Norazalina, et al.
Published: (2018)

Breast cancer prognostic classifiers: combining clinical with molecular profiles
by: Muftah, Abir A. Abdelhadi
Published: (2017)

Circulating microRNAs for the prediction of metastasis in breast cancer patients diagnosed with early stage disease
by: Inns, Joseph, et al.
Published: (2015)

Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC
by: Kaewkangsadan, Viriya, et al.
Published: (2016)

Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC
by: Kaewkangsadan, Viriya, et al.
Published: (2018)

RECQL4 helicase has oncogenic potential in sporadic breast cancers
by: Arora, Arvind, et al.
Published: (2016)

Prognostic significance of Glutamine-Related Solute Carriers in luminal breast cancer
by: Erkan, Busra
Published: (2025)

Morphological and transcriptome characterisation of salivary glands of edible bird nests-producing swiftlets
by: Looi, Qi Hao
Published: (2016)

Behavioural determinants of ranchers towards sustainable edible-nest swiftlet ranching in Malaysia
by: K N Vaiappuri, Selvakkumar
Published: (2017)

Development of a clinically relevant subclassification of luminal breast cancer related to response to endocrine therapy
by: Alfarsi, Lutfi
Published: (2020)

Nutritional analysis, metabolomics and proteomics of edible bird nest from different georaphical regions of Malaysia
by: Zulkifli, Danish Adli
Published: (2018)

Unravelling the tumour- and cancer stem cell (CSC)-regulatory roles of miR-3934-5p in human breast cancer
by: Chong, Zhi Xiong
Published: (2024)

Long-term speech and language deficits and associated neural correlates in survivors of paediatric posterior fossa tumours
by: Hodgson, Olha
Published: (2018)

Role of tumour microenvironment in the development of lymphovascular invasion in breast cancer
by: Lakshmi Narasimha, Pavan
Published: (2020)

CLIC1 and CLIC4 ion channels as therapeutic targets for tumour treating fields in paediatric high grade glioma
by: Griffin, Michaela
Published: (2023)

An RNAi-mediated genetic screen identifies genes that promote tumour progression in a living epithelium
by: Cornhill, Zoe
Published: (2017)

IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients
by: Ahmad, Narmeen, et al.
Published: (2018)

Biology and clinical outcomes of early primary breast cancer in older women: a study based on core needle biopsy
by: Albanghali, Mohammad
Published: (2016)

Neurodevelopmental outcome following cerebellar tumour sustained in early childhood
by: Davis, Emma E.
Published: (2011)

Targeting tumour-astrocyte crosstalk for rational identification of novel therapeutic targets for atypical Teratoid/ Rhabdoid tumours
by: Porter, Harry
Published: (2025)

Integrating transcriptomics and metabolomics to analyse and target tumour heterogeneity in paediatric ependymoma
by: Pandele, Alina Gabriela
Published: (2024)

Characterization and primary recovery of funtional bioactive compounds from edible bird's nest
by: Lim, Hong Kwong
Published: (2014)

Histopathological assessment of acetaminophen-induced liver injury and regeneration response following edible bird’s nest administration in ICR and BALB/C mice model
by: Fazil, Muhammad Azam
Published: (2021)