Matrix metalloproteinase-1 mediated extra-cellular matrix remodelling contributes to airway smooth muscle growth and asthma severity
Introduction Airway remodelling describes the histopathological changes in tissue architecture observed in obstructive lung diseases such as asthma and may have a negative impact on lung function. These changes do not appear to be treated by current asthma treatments. Changes observed during airw...
| Main Author: | Naveed, Shams-un-nisa |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/50577/ |
Similar Items
MMP-1 activation contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa, et al.
Published: (2017)
by: Naveed, Shams-un-nisa, et al.
Published: (2017)
An in vitro and in silico study of altered airway smooth muscle structure and function in a remodelled asthmatic airway
by: Brown, Sarah
Published: (2023)
by: Brown, Sarah
Published: (2023)
Aberrant DNA methylation and its regulation of gene expression in airway smooth muscle cells of individuals with asthma
by: Clifford, Rachel Louise
Published: (2023)
by: Clifford, Rachel Louise
Published: (2023)
The role of histone arginine methylation in cytokine/chemokine gene expression in airway smooth muscle cells in asthma
by: Kaczmarek, Klaudia
Published: (2019)
by: Kaczmarek, Klaudia
Published: (2019)
Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment
by: Alcantara, M., et al.
Published: (2014)
by: Alcantara, M., et al.
Published: (2014)
Modelling cell–matrix interactions in airway smooth muscle cells
by: Irons, Linda
Published: (2019)
by: Irons, Linda
Published: (2019)
The differential effects of azithromycin on the airway epithelium in vitro and in vivo
by: Slater, Mariel, et al.
Published: (2016)
by: Slater, Mariel, et al.
Published: (2016)
Association of matrix metalloproteinase-1, 9, 12 and tissue inhibitor of metalloproteinase-1 gene polymorphisms in malay male essential hypertensive subject
by: Tabatabaee, Farizeh Aalam Ghomi
Published: (2015)
by: Tabatabaee, Farizeh Aalam Ghomi
Published: (2015)
Utility of the precision cut lung slice model to investigate airway smooth muscle contraction
by: Fox, Jane
Published: (2011)
by: Fox, Jane
Published: (2011)
In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss
by: Chernyavsky, Igor L., et al.
Published: (2018)
by: Chernyavsky, Igor L., et al.
Published: (2018)
Effect of cigarette smoke extract on inflammatory cytokine production and corticosteroid insensitivity in human airway smooth muscle cells
by: Alahmari, Mushabbab
Published: (2022)
by: Alahmari, Mushabbab
Published: (2022)
Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma
by: Middlewick, Robert James
Published: (2020)
by: Middlewick, Robert James
Published: (2020)
Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity
by: Singh, Shailendra R., et al.
Published: (2014)
by: Singh, Shailendra R., et al.
Published: (2014)
Cytotoxic Effect of Betulinic Acid on Vascular Smooth Muscle Cells
by: Vadivelu, Raja Kumar
Published: (2009)
by: Vadivelu, Raja Kumar
Published: (2009)
Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma
by: Donovan, G.M., et al.
Published: (2020)
by: Donovan, G.M., et al.
Published: (2020)
Influencing the degradation rate of recombinant spider silk in the presence of matrix metalloproteinases
by: Coekin, Thomas
Published: (2021)
by: Coekin, Thomas
Published: (2021)
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone
by: Alcantara, M., et al.
Published: (2014)
by: Alcantara, M., et al.
Published: (2014)
Airway and parenchymal strains during bronchoconstriction in the precision cut lung slice
by: Hiorns, Jonathan E., et al.
Published: (2016)
by: Hiorns, Jonathan E., et al.
Published: (2016)
Attenuation of urokinase activity during experimental ischaemia protects the cerebral barrier from damage through regulation of matrix metalloproteinase-2 and NAD(P)H oxidase
by: Rakkar, Kamini, et al.
Published: (2014)
by: Rakkar, Kamini, et al.
Published: (2014)
Airway remodeling blockade with an orally active geranyl acetophenone
by: Lee, Yu Zhao
Published: (2017)
by: Lee, Yu Zhao
Published: (2017)
Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells
by: Gough, Kevin C., et al.
Published: (2015)
by: Gough, Kevin C., et al.
Published: (2015)
Matrix Metalloproteinase -9 and Tissue Inhibitors of Metalloproteinasr-1 and -2 as Potential Novel Biomakers in Gestational Hypertension
by: Ab Hamid, Jabrullah
Published: (2010)
by: Ab Hamid, Jabrullah
Published: (2010)
Development of a magnetic resonance imaging biomarker to improve prognostication in metastatic medulloblastoma
by: Mitoko, Christine Angeline
Published: (2021)
by: Mitoko, Christine Angeline
Published: (2021)
Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations
by: Franchi, Martino V., et al.
Published: (2017)
by: Franchi, Martino V., et al.
Published: (2017)
Liver progenitor cell interactions with the extracellular matrix
by: Zhu, C., et al.
Published: (2012)
by: Zhu, C., et al.
Published: (2012)
Parametric solutions to Sylvester conjugate matrix equations
by: Wu, A., et al.
Published: (2011)
by: Wu, A., et al.
Published: (2011)
Investigating the role of tumour-deposited extracellular matrix in medulloblastoma progression
by: Johnson, James E. C.
Published: (2023)
by: Johnson, James E. C.
Published: (2023)
Mechanisms of transforming growth factor-β activation in airway smooth muscle cells and its role in asthma
by: Tatler, Amanda Louise
Published: (2010)
by: Tatler, Amanda Louise
Published: (2010)
Bio-responsive hydrogels for an in vitro brain cancer cell model: self-controlled inhibition of matrix metalloproteinase activity
by: Russo, Emanuele
Published: (2020)
by: Russo, Emanuele
Published: (2020)
Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma
by: Rogers, Natasha K., et al.
Published: (2014)
by: Rogers, Natasha K., et al.
Published: (2014)
Mathematical Models of Pro-remodelling Growth Factor Activation in Asthmatic Airways
by: Pybus, Hannah J.
Published: (2020)
by: Pybus, Hannah J.
Published: (2020)
Direct predictive current-error vector control for a direct matrix converter
by: Vijayagopal, Manjusha, et al.
Published: (2019)
by: Vijayagopal, Manjusha, et al.
Published: (2019)
Development and application of minimally invasive stable isotope tracers’ measures of muscle mass and muscle protein synthesis/breakdown: insights into ageing skeletal muscle
by: Cegielski, Jessica
Published: (2020)
by: Cegielski, Jessica
Published: (2020)
Evaluation of osteogenic potential of demineralized bone matrix in pigeon (Columba livia Gmelin)
by: Sanaei, Mohamad Reza
Published: (2011)
by: Sanaei, Mohamad Reza
Published: (2011)
A review of predictive control techniques for matrix converters: part I
by: Rivera, Marco, et al.
Published: (2016)
by: Rivera, Marco, et al.
Published: (2016)
A review of predictive control techniques for matrix converters: part II
by: Rivera, Marco, et al.
Published: (2016)
by: Rivera, Marco, et al.
Published: (2016)
The transcriptional regulation of VEGF production from pulmonary artery smooth muscle cells by TGFβ1
by: Clifford, Rachel
Published: (2009)
by: Clifford, Rachel
Published: (2009)
Nonlinear development of matrix-converter instabilities
by: Cox, Stephen M., et al.
Published: (2009)
by: Cox, Stephen M., et al.
Published: (2009)
Human muscle weakness and fatigue: the effects of disuse, age and exercise
by: White, Michael J.
Published: (1987)
by: White, Michael J.
Published: (1987)
A hybrid indirect matrix converter immune to unbalanced voltage supply, with reduced switching losses and improved voltage transfer ratio
by: Klumpner, Christian
Published: (2005)
by: Klumpner, Christian
Published: (2005)
Similar Items
-
MMP-1 activation contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa, et al.
Published: (2017) -
An in vitro and in silico study of altered airway smooth muscle structure and function in a remodelled asthmatic airway
by: Brown, Sarah
Published: (2023) -
Aberrant DNA methylation and its regulation of gene expression in airway smooth muscle cells of individuals with asthma
by: Clifford, Rachel Louise
Published: (2023) -
The role of histone arginine methylation in cytokine/chemokine gene expression in airway smooth muscle cells in asthma
by: Kaczmarek, Klaudia
Published: (2019) -
Pigment epithelium-derived factor as a natural matrix metalloproteinase inhibitor: a comparison with classical matrix metalloproteinase inhibitors used for cancer treatment
by: Alcantara, M., et al.
Published: (2014)