Enhanced uptake in 2D- and 3D- lung cancer cell models of redox responsive PEGylated nanoparticles with sensitivity to reducing extra-and intracellular environments

QR Code

Enhanced uptake in 2D- and 3D- lung cancer cell models of redox responsive PEGylated nanoparticles with sensitivity to reducing extra-and intracellular environments

In the treatment of lung cancer, there is an urgent need of innovative medicines to optimize pharmacological responses of conventional chemotherapeutics while attenuating side effects. Here, we have exploited some relatively unexplored subtle differences in reduction potential, associated with cance...

Full description

Bibliographic Details
Main Authors:	Conte, Claudia, Mastrotto, Francesca, Taresco, Vincenzo, Tchoryk, Aleksandra, Quaglia, Fabiana, Stolnik, Snjezana, Alexander, Cameron
Format:	Article
Language:	English English
Published:	Elsevier 2018
Online Access:	https://eprints.nottingham.ac.uk/50374/

Similar Items

Rapid formulation of redox-responsive oligo-β-aminoester polyplexes with siRNA via jet printing
by: Lovato, Tatiana, et al.
Published: (2018)

3D spheroid models for in vitro evaluation of nanoparticles for cancer therapy
by: Tchoryk, Aleksandra
Published: (2018)

Structural variations in hyperbranched polymers prepared via thermal polycondensation of lysine and histidine and their effects on DNA delivery
by: Alazzo, Ali, et al.
Published: (2018)

Na+/H+ exchanger 1 (NHE-1) redox-regulated gene and intracellular target for the redox control of cell death sensitivity
by: Akram, S., et al.
Published: (2011)

PEGylation of paclitaxel for inhaled chemotherapy
by: Luo, Tian
Published: (2016)

Water solubility enhancement of pyrazolo[3,4-d]pyrimidine derivatives via miniaturized polymer-drug microarrays
by: Sanna, Monica, et al.
Published: (2018)

Pegylated granulocyte colony stimulating factor versus non-pegylated granulocyte colony stimulating factor for peripheral stem cell mobilization
by: Kuan, Jewwin, et al.
Published: (2016)

Penetration and intracellular uptake of poly(glycerol-adipate)nanoparticles into 3-dimensional brain tumour cell culture models
by: Meng, Weina, et al.
Published: (2016)

Natural quinones and their analogues: synthesis, intracellular redox cycling and identification of indoleamine-2,3-dioxygenase (IDO) as a potential target for anticancer activity
by: Blunt, Christopher, et al.
Published: (2015)

Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter
by: Kostrycki, I., et al.
Published: (2019)

Redox-responsive chemosensitive polyspermine delivers ursolic acid targeting to human breast tumor cells: The depletion of intracellular GSH contents arouses chemosensitizing effects
by: Ji, X., et al.
Published: (2018)

PEGylation of PLGA and PCL nanoparticles enhanced the cytotoxicity of loaded 5-flurouracil
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2017)

Quantification and qualitative effects of different PEGylations on Poly(butyl cyanoacrylate) nanoparticles
by: Aslund, Andreas K.O, et al.
Published: (2017)

PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy
by: Osman, Gizem, et al.
Published: (2018)

Facilitated water-selective permeation via PEGylation of graphene oxide membrane
by: Zhao, D., et al.
Published: (2018)

PEGylated Oleic Acid-Lecithin Liposomes (POLL) for anticancer drug delivery
by: Vicit Rizal Eh Suk,, et al.
Published: (2020)

Dynamics of PEGylated-dextran-spermine nanoparticles for gene delivery to leukemic cells.
by: Amini, Razieh, et al.
Published: (2013)

Hydrophobically Modified Pegylated Chitosan Derivative: Synthesis, Characterisation And Formulation Of Nanoparticles
by: Chong, Wai Mun
Published: (2021)

Pegylated Phospholipid Nanomicelles Containing Budesonide Or Beclimethasone Dipropionate For Pulmonary Delivery
by: Sahib, Mohanad Naji
Published: (2011)

Uptake and transport of B12-conjugated nanoparticles in airway epithelium
by: Fowler, Robyn, et al.
Published: (2013)

Extra home-office
by: Tan, Kok Hang, et al.
Published: (2013)

Take extra precautions
by: Pfordten, Diyana
Published: (2021)

Stimuli-responsive prodrug chemistries for drug delivery
by: Taresco, Vincenzo, et al.
Published: (2018)

Light-Induced Cytochrome c Redox Mediated Cell Killing
by: Potts, Jordan Cameron
Published: (2023)

Intracellular delivery of therapeutic antibodies
by: Hackett, Gavin S.
Published: (2012)

Modelling of intracellular calcium dynamics
by: Tilūnaitė, Agnė
Published: (2018)

Physical pegylation enhances the cytotoxicity of 5-fluorouracil-loaded PLGA And PCL nanoparticles.
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)

Mechanisms of retention of PEGylated recombinant human deoxyribonuclease i (rhDNase) in the lungs
by: Mahri, Sohaib
Published: (2021)

Factors influencing the synthesis and the post-modification of PEGylated pentafluorophenyl acrylate containing copolymers
by: Beija, M., et al.
Published: (2013)

Luminescent Bimetallic d-f Complexes
by: Cameron, Lee John
Published: (2024)

Control of aggregation temperatures in mixed and blended cytocompatible thermoresponsive block co-polymer nanoparticles
by: Foralosso, Ruggero, et al.
Published: (2017)

Extra Ear: Ear on Arm
by: Stelarc, Stelarc
Published: (2008)

Extra Ear and Extended Arm
by: Stelarc, Stelarc
Published: (2009)

An ion pairing approach to increase the loading of hydrophilic and lipophilic drugs into PEGylated PLGA nanoparticles
by: Dalwadi, G., et al.
Published: (2009)

Design, syntheses and evaluation of hemocompatible pegylated-antimicrobial polymers with well-controlled molecular structures
by: Venkataraman, S., et al.
Published: (2010)

Synthesis And Characterisation Of Pegylated Gold Nanoparticles For Enhancement Of Agglutination Reaction In Antibody Screening Test
by: Ishak, Nordiyana
Published: (2024)

Translating intracellular calcium signaling into models
by: Thul, Ruediger
Published: (2014)

A method for purification of intracellular protein.
by: Tey, Beng Ti, et al.
Published: (2009)

Role of vitamin D and E in modulating glucose uptake and insulin sensitivity in insulin-resistant neuronal cells
by: Zaulkffali, Amirah Salwani
Published: (2017)

Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery
by: Louzao, Iria, et al.
Published: (2018)