Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis

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Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis

Chemotherapy-induced hemorrhagic cystitis (CHC) can be difficult to manage. Prior work suggests IL-4 alleviates ifosfamide-induced hemorrhagic cystitis (IHC), but systemically administered IL-4 causes significant side effects. We hypothesized that the Schistosoma haematobium homolog of Interleukin-4...

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Bibliographic Details
Main Authors:	Mbanefo, Evaristus C., Le, Loc, Pennington, Luke F., Odegaard, Justin I., Jardetzky, Theodore S., Alouffi, Abdulaziz, Falcone, Franco H., Hsieh, Michael H.
Format:	Article
Language:	English
Published:	Federation of American Society of Experimental Biology 2018
Subjects:	Infiltrin; Anti-inflammation; Ifosfamide; Allodynia; Urothelial repair
Online Access:	https://eprints.nottingham.ac.uk/50318/

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