Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons

Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons

Metabolite profiling is an important tool that may better capture the multiple features of neurodegeneration. With the considerable parallels between mouse and human metabolism, the use of metabolomics in mouse models with neurodegenerative pathology provides mechanistic insight and ready translatio...

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Bibliographic Details
Main Authors: Geiszler, Philippine C., Ugun-Klusek, Aslihan, Lawler, Karen, Pardon, Marie-Christine, Yuchun, Ding, Bai, Li, Daykin, Clare, Auer, Dorothee P., Bedford, Lynn
Format: Article
Language:English
Published: Nature Publishing Group 2018
Online Access:https://eprints.nottingham.ac.uk/50317/

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