An examination of appetite and disordered eating in active Crohn’s disease
Background: Crohn’s disease (CD) patients suffer from nutritional deficiencies when in active disease. We aim to examine calorific intake, macronutrient choice and disordered eating behaviour in patients with active CD. Methods: CD patients with matched healthy volunteers (HV) were recruited. Acti...
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| Format: | Article |
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Oxford University Press
2018
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| Online Access: | https://eprints.nottingham.ac.uk/50279/ |
| _version_ | 1848798207734185984 |
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| author | Wardle, Richard Thapaliya, Gita Nowak, Adam Radford, Shellie Dalton, Michelle Finlayson, Graham Moran, Gordon W. |
| author_facet | Wardle, Richard Thapaliya, Gita Nowak, Adam Radford, Shellie Dalton, Michelle Finlayson, Graham Moran, Gordon W. |
| author_sort | Wardle, Richard |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: Crohn’s disease (CD) patients suffer from nutritional deficiencies when in active disease. We aim to examine calorific intake, macronutrient choice and disordered eating behaviour in patients with active CD.
Methods: CD patients with matched healthy volunteers (HV) were recruited. Active disease was defined by faecal calprotectin >250ug/g, C-reactive protein >5mg/dl, or active disease seen on endoscopy or imaging. Symptoms were quantified by Harvey-Bradshaw Index (HBI). Calorific intake was assessed by 24-h dietary recall. Disordered eating was assessed using validated questionnaires [Binge Eating Scale (BES); Power of Food Scale (PFS); Control of Eating Questionnaire (CoEQ); Dutch Eating Behaviour Questionnaire (DEBQ); Three Factor Eating Questionnaire (TFEQ)].
Results: 30 CD (18M:12F, Age:32.3±2.19, BMI:24.9±0.8) and 31 matched HV (19M:12F, Age:32.8±2.0, BMI:24.7±0.5) were recruited. Mean faecal calprotectin was 1032.5±176µg/g,C-reactive protein 83.8±47.1mg/L and HBI 4.8±1. There were no significant differences in calorific intake between groups. Protein intake was lower in the CD cohort (p=0.03). Hospital Anxiety and Depression score was higher (p=0.01) and CoEQ-Positive Mood (p=0.001) lower in CD. CD were characterised by higher BES (p=0.01) and lower CoEQ Craving Control (p=0.027) with greater craving for Sweet (p=0.043), Savoury (p=0.021) foods. PFS food present (p=0.005), DEBQ Emotional (p=<0.001) and External Eating (p=0.022) were significantly higher than HV.
Conclusions: Reduced protein consumption and more prevalent disordered eating behaviour traits were present in CD. Greater binge eating and decreased control of cravings may be attributed to lower mood and higher anxiety observed. Patients may benefit from stronger psychological support with firm dietetic advice for healthy eating. |
| first_indexed | 2025-11-14T20:16:06Z |
| format | Article |
| id | nottingham-50279 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:16:06Z |
| publishDate | 2018 |
| publisher | Oxford University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-502792024-08-15T15:30:24Z https://eprints.nottingham.ac.uk/50279/ An examination of appetite and disordered eating in active Crohn’s disease Wardle, Richard Thapaliya, Gita Nowak, Adam Radford, Shellie Dalton, Michelle Finlayson, Graham Moran, Gordon W. Background: Crohn’s disease (CD) patients suffer from nutritional deficiencies when in active disease. We aim to examine calorific intake, macronutrient choice and disordered eating behaviour in patients with active CD. Methods: CD patients with matched healthy volunteers (HV) were recruited. Active disease was defined by faecal calprotectin >250ug/g, C-reactive protein >5mg/dl, or active disease seen on endoscopy or imaging. Symptoms were quantified by Harvey-Bradshaw Index (HBI). Calorific intake was assessed by 24-h dietary recall. Disordered eating was assessed using validated questionnaires [Binge Eating Scale (BES); Power of Food Scale (PFS); Control of Eating Questionnaire (CoEQ); Dutch Eating Behaviour Questionnaire (DEBQ); Three Factor Eating Questionnaire (TFEQ)]. Results: 30 CD (18M:12F, Age:32.3±2.19, BMI:24.9±0.8) and 31 matched HV (19M:12F, Age:32.8±2.0, BMI:24.7±0.5) were recruited. Mean faecal calprotectin was 1032.5±176µg/g,C-reactive protein 83.8±47.1mg/L and HBI 4.8±1. There were no significant differences in calorific intake between groups. Protein intake was lower in the CD cohort (p=0.03). Hospital Anxiety and Depression score was higher (p=0.01) and CoEQ-Positive Mood (p=0.001) lower in CD. CD were characterised by higher BES (p=0.01) and lower CoEQ Craving Control (p=0.027) with greater craving for Sweet (p=0.043), Savoury (p=0.021) foods. PFS food present (p=0.005), DEBQ Emotional (p=<0.001) and External Eating (p=0.022) were significantly higher than HV. Conclusions: Reduced protein consumption and more prevalent disordered eating behaviour traits were present in CD. Greater binge eating and decreased control of cravings may be attributed to lower mood and higher anxiety observed. Patients may benefit from stronger psychological support with firm dietetic advice for healthy eating. Oxford University Press 2018-06-28 Article PeerReviewed Wardle, Richard, Thapaliya, Gita, Nowak, Adam, Radford, Shellie, Dalton, Michelle, Finlayson, Graham and Moran, Gordon W. (2018) An examination of appetite and disordered eating in active Crohn’s disease. Journal of Crohn's and Colitis, 12 (7). pp. 819-825. ISSN 1876-4479 Inflammatory Bowel Disease Crohn’s disease eating behaviour nutrition https://academic.oup.com/ecco-jcc/advance-article/doi/10.1093/ecco-jcc/jjy041/4959791 doi:10.1093/ecco-jcc/jjy041 doi:10.1093/ecco-jcc/jjy041 |
| spellingShingle | Inflammatory Bowel Disease Crohn’s disease eating behaviour nutrition Wardle, Richard Thapaliya, Gita Nowak, Adam Radford, Shellie Dalton, Michelle Finlayson, Graham Moran, Gordon W. An examination of appetite and disordered eating in active Crohn’s disease |
| title | An examination of appetite and disordered eating in active Crohn’s disease |
| title_full | An examination of appetite and disordered eating in active Crohn’s disease |
| title_fullStr | An examination of appetite and disordered eating in active Crohn’s disease |
| title_full_unstemmed | An examination of appetite and disordered eating in active Crohn’s disease |
| title_short | An examination of appetite and disordered eating in active Crohn’s disease |
| title_sort | examination of appetite and disordered eating in active crohn’s disease |
| topic | Inflammatory Bowel Disease Crohn’s disease eating behaviour nutrition |
| url | https://eprints.nottingham.ac.uk/50279/ https://eprints.nottingham.ac.uk/50279/ https://eprints.nottingham.ac.uk/50279/ |