Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial
Objective Fractured neck of femur is a severely painful condition with significant mortality and morbidity. We investigated whether early and continuous use of femoral nerve block can improve pain on movement and mobility after surgery in older participants with fragility neck of femur fracture....
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group Ltd
2018
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| Online Access: | https://eprints.nottingham.ac.uk/50162/ |
| _version_ | 1848798172139225088 |
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| author | Rowlands, Martin Walt, Gerrie van de Bradley, Jim Mannings, Alexa Armstrong, Sarah Bedforth, Nigel M. Moppett, Iain K. Sahota, Opinder |
| author_facet | Rowlands, Martin Walt, Gerrie van de Bradley, Jim Mannings, Alexa Armstrong, Sarah Bedforth, Nigel M. Moppett, Iain K. Sahota, Opinder |
| author_sort | Rowlands, Martin |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Objective
Fractured neck of femur is a severely painful condition with significant mortality and morbidity. We investigated whether early and continuous use of femoral nerve block can improve pain on movement and mobility after surgery in older participants with fragility neck of femur fracture.
Design
Prospective single centre, randomised controlled pragmatic trial.
Setting
Secondary care, acute NHS Trust, UK.
Participants
Participants admitted with a history and examination suggesting fractured neck of femur.
Intervention
Immediate continuous femoral nerve block via catheter or standard analgesia.
Results
One hundred and forty one participants were recruited, with 23 excluded. No significant difference was detected between cumulative dynamic pain scores (standard care (n = 56) vs 4
intervention (n = 55) 20 (IQR 15-24) vs 20 (15-23) p=0.51) or cumulated ambulation scores (standard care vs intervention 6 (5-9) vs 7 (5-10) p=0.76). There were no statistically different differences in secondary outcomes except cumulative pain at rest: 5 (0.5-6.5) in the standard care group and 2 (0-5) in the intervention group (p=0.043).
Conclusions
Early application of continuous femoral nerve block compared with standard systemic analgesia did not result in improved dynamic pain scores or superior post-operative ambulation. This technique may provide superior pain relief at rest. Continuous femoral nerve block did not delay initial control of pain, or mobilisation after surgery. |
| first_indexed | 2025-11-14T20:15:32Z |
| format | Article |
| id | nottingham-50162 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T20:15:32Z |
| publishDate | 2018 |
| publisher | BMJ Publishing Group Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-501622018-04-15T22:18:40Z https://eprints.nottingham.ac.uk/50162/ Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial Rowlands, Martin Walt, Gerrie van de Bradley, Jim Mannings, Alexa Armstrong, Sarah Bedforth, Nigel M. Moppett, Iain K. Sahota, Opinder Objective Fractured neck of femur is a severely painful condition with significant mortality and morbidity. We investigated whether early and continuous use of femoral nerve block can improve pain on movement and mobility after surgery in older participants with fragility neck of femur fracture. Design Prospective single centre, randomised controlled pragmatic trial. Setting Secondary care, acute NHS Trust, UK. Participants Participants admitted with a history and examination suggesting fractured neck of femur. Intervention Immediate continuous femoral nerve block via catheter or standard analgesia. Results One hundred and forty one participants were recruited, with 23 excluded. No significant difference was detected between cumulative dynamic pain scores (standard care (n = 56) vs 4 intervention (n = 55) 20 (IQR 15-24) vs 20 (15-23) p=0.51) or cumulated ambulation scores (standard care vs intervention 6 (5-9) vs 7 (5-10) p=0.76). There were no statistically different differences in secondary outcomes except cumulative pain at rest: 5 (0.5-6.5) in the standard care group and 2 (0-5) in the intervention group (p=0.043). Conclusions Early application of continuous femoral nerve block compared with standard systemic analgesia did not result in improved dynamic pain scores or superior post-operative ambulation. This technique may provide superior pain relief at rest. Continuous femoral nerve block did not delay initial control of pain, or mobilisation after surgery. BMJ Publishing Group Ltd 2018-04-10 Article PeerReviewed application/pdf en cc_by_nc https://eprints.nottingham.ac.uk/50162/8/e019650.full.pdf Rowlands, Martin, Walt, Gerrie van de, Bradley, Jim, Mannings, Alexa, Armstrong, Sarah, Bedforth, Nigel M., Moppett, Iain K. and Sahota, Opinder (2018) Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial. BMJ Open, 8 (4). e019650/1-e019650/8. ISSN 2044-6055 Femoral nerve block; Hip fracture; Regional anaesthesia; Pain control; Older people http://bmjopen.bmj.com/content/8/4/e019650 doi:10.1136/bmjopen-2017-019650 doi:10.1136/bmjopen-2017-019650 |
| spellingShingle | Femoral nerve block; Hip fracture; Regional anaesthesia; Pain control; Older people Rowlands, Martin Walt, Gerrie van de Bradley, Jim Mannings, Alexa Armstrong, Sarah Bedforth, Nigel M. Moppett, Iain K. Sahota, Opinder Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial |
| title | Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial |
| title_full | Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial |
| title_fullStr | Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial |
| title_full_unstemmed | Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial |
| title_short | Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial |
| title_sort | femoral nerve block intervention in neck of femur fracture (finof): a randomized controlled trial |
| topic | Femoral nerve block; Hip fracture; Regional anaesthesia; Pain control; Older people |
| url | https://eprints.nottingham.ac.uk/50162/ https://eprints.nottingham.ac.uk/50162/ https://eprints.nottingham.ac.uk/50162/ |