Delivery of inhibitory signalling via co-crosslinking of FcεRI and FcγRIIB with engineered micro-surfaces as a new therapeutic concept

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Delivery of inhibitory signalling via co-crosslinking of FcεRI and FcγRIIB with engineered micro-surfaces as a new therapeutic concept

Mast cell and basophil mediators play a major role in the development of immunoglobulin E (IgE)-dependent allergic disorders. One of these mediators is histamine, which is released by activation of inflammatory cells through cross-linking of the high affinity IgE receptor (FcεRI). The current immuno...

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Bibliographic Details
Main Author:	Alharbi, Waleed S.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	Allergy Mast cells Basophils FcεRI FcγRIIB
Online Access:	https://eprints.nottingham.ac.uk/50086/

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