Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy.

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Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy.

Raman microscopy was used as a label-free method to study the mineralisation of bone nodules formed by mesenchymal stem cells cultured in osteogenic medium in vitro. Monitoring individual bone nodules over 28 days revealed temporal and spatial changes in the crystalline phase of the hydroxyapatite c...

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Bibliographic Details
Main Authors:	Ghita, Adrian, Pascut, Flavius C., Sottile, Virginie, Notingher, Ioan
Format:	Article
Language:	English
Published:	Royal Society of Chemistry 2013
Online Access:	https://eprints.nottingham.ac.uk/49915/

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