Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach

Objective To explore stakeholder perspectives upon participant retention in clinical trials, and to generate strategies to support retention in a surgical, clinical trial. Study Design & Setting The SWIFFT trial is a multi-centre study comparing treatments for the fracture of the wais...

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Main Authors: Leighton, Paul, Brealey, Stephen D., Dias, Joseph J.
Format: Article
Published: Wiley 2018
Online Access:https://eprints.nottingham.ac.uk/49907/
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author Leighton, Paul
Brealey, Stephen D.
Dias, Joseph J.
author_facet Leighton, Paul
Brealey, Stephen D.
Dias, Joseph J.
author_sort Leighton, Paul
building Nottingham Research Data Repository
collection Online Access
description Objective To explore stakeholder perspectives upon participant retention in clinical trials, and to generate strategies to support retention in a surgical, clinical trial. Study Design & Setting The SWIFFT trial is a multi-centre study comparing treatments for the fracture of the waist of the scaphoid bone in adults. Here we report upon a multi-stage, iterative consultative process with SWIFFT stakeholders, these include workshops with members of the public, with nurses involved in data collection, and with consultant clinicians. Structured discussions were digitally recorded and transcribed, data were handled and analysed following a framework approach to qualitative data analysis. Results Removing practical barriers were identified as important factors in supporting retention. Stakeholders also identified that i) how well a study is understood and ii) how much it is valued are important factors in an individual’s willingness to maintain their involvement. A number of strategies resulted from this consultation, these include: in-clinic data collection, co-ordinated clinical and research appointments, a SWIFFT website and newsletter. Conclusion A participatory approach to trial retention might engage all relevant stakeholders in the delivery of a clinical trial, it might also support the generation of specific and contextually relevant solutions to the challenge of participant retention.
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spelling nottingham-499072020-05-04T19:27:52Z https://eprints.nottingham.ac.uk/49907/ Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach Leighton, Paul Brealey, Stephen D. Dias, Joseph J. Objective To explore stakeholder perspectives upon participant retention in clinical trials, and to generate strategies to support retention in a surgical, clinical trial. Study Design & Setting The SWIFFT trial is a multi-centre study comparing treatments for the fracture of the waist of the scaphoid bone in adults. Here we report upon a multi-stage, iterative consultative process with SWIFFT stakeholders, these include workshops with members of the public, with nurses involved in data collection, and with consultant clinicians. Structured discussions were digitally recorded and transcribed, data were handled and analysed following a framework approach to qualitative data analysis. Results Removing practical barriers were identified as important factors in supporting retention. Stakeholders also identified that i) how well a study is understood and ii) how much it is valued are important factors in an individual’s willingness to maintain their involvement. A number of strategies resulted from this consultation, these include: in-clinic data collection, co-ordinated clinical and research appointments, a SWIFFT website and newsletter. Conclusion A participatory approach to trial retention might engage all relevant stakeholders in the delivery of a clinical trial, it might also support the generation of specific and contextually relevant solutions to the challenge of participant retention. Wiley 2018-01-22 Article PeerReviewed Leighton, Paul, Brealey, Stephen D. and Dias, Joseph J. (2018) Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach. Journal of Evidence-Based Medicine . ISSN 1756-5391 http://onlinelibrary.wiley.com/doi/10.1111/jebm.12271/full doi:10.1111/jebm.12271 doi:10.1111/jebm.12271
spellingShingle Leighton, Paul
Brealey, Stephen D.
Dias, Joseph J.
Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach
title Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach
title_full Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach
title_fullStr Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach
title_full_unstemmed Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach
title_short Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach
title_sort interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach
url https://eprints.nottingham.ac.uk/49907/
https://eprints.nottingham.ac.uk/49907/
https://eprints.nottingham.ac.uk/49907/