Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics

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Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics

Understanding the roles of ion currents is crucial to predict the action of pharmaceuticals and mutations in different scenarios, and thereby to guide clinical interventions in the heart, brain and other electrophysiological systems. Our ability to predict how ion currents contribute to cellular ele...

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Bibliographic Details
Main Authors:	Beattie, Kylie, Hill, Adam P., Bardenet, Rémi, Cui, Yi, Vandenberg, Jamie I., Gavaghan, David J., de Boer, Teun P., Mirams, Gary R.
Format:	Article
Published:	Wiley 2018
Subjects:	hERG IKr mathematical model electrophysiology patch clamp voltage protocol
Online Access:	https://eprints.nottingham.ac.uk/49871/

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