A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells

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A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells

Purpose Glioblastoma Multiforme (GBM) is the commonest brain tumour in adults. A population of cells, known as cancer stem cells (CSCs), is thought to mediate chemo/radiotherapy resistance. CD133 is a cell surface marker to identify and isolate CSCs. However, its functional significance and the...

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Bibliographic Details
Main Authors:	Ahmed, Eroje M., Bandopadhyay, Gagori, Coyle, Beth, Grabowska, Anna M.
Format:	Article
Published:	Springer 2018
Subjects:	Hypoxia; Cisplatin; Temozolomide; Chemoresistance; CD133; HIFs
Online Access:	https://eprints.nottingham.ac.uk/49861/

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