Mechanism of subunit interaction at ketosynthase-dehydratase junctions in trans-AT polyketide synthases

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Mechanism of subunit interaction at ketosynthase-dehydratase junctions in trans-AT polyketide synthases

Modular polyketide synthases (PKSs) produce numerous structurally complex natural products with diverse applications in medicine and agriculture. They typically consist of several multienzyme subunits that utilize structurally-defined docking domains (DDs) at their N- and C-termini to ensure correct...

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Bibliographic Details
Main Authors:	Jenner, Matthew, Kosol, Simone, Griffiths, Daniel, Prasongpholchai, Panward, Manzi, Lucio, Barrow, Andrew S., Moses, John E., Oldham, Neil J., Lewandowski, Jozef, Challis, Gregory
Format:	Article
Published:	Nature Publishing Group 2018
Online Access:	https://eprints.nottingham.ac.uk/49829/

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