Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials

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Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials

Antimalarial drug resistance hampers effective malaria treatment. Critical SNPs in a particular, putative amino acid transporter were recently linked to chloroquine (CQ) resistance in malaria parasites. Here, we show that this conserved protein (PF3D7_0629500 in Plasmodium falciparum; AAT1 in P. cha...

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Bibliographic Details
Main Authors:	Tindall, Sarah M., Vallières, Cindy, Lakhani, Dev H., Islahudin, Farida, Ting, Kang-Nee, Avery, Simon V.
Format:	Article
Published:	Nature Publishing Group 2018
Online Access:	https://eprints.nottingham.ac.uk/49646/

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