Production of a sustainable primary airway cell model for respiratory research

QR Code

Production of a sustainable primary airway cell model for respiratory research

The airway epithelium is one of the body’s front-line defences against environmental factors. It is known that in diseases such as asthma and COPD the epithelial layer is susceptible to damage which propagates inflammation and airway remodelling. Whilst primary airway epithelial cells have been key...

Full description

Bibliographic Details
Main Author:	O'Loughlin, Jonathan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	BMI-1; Bronchial epithelial cells; Lentivirus; Cell culture
Online Access:	https://eprints.nottingham.ac.uk/49344/

Similar Items

Development of a sustainable primary human airway cell culture model for respiratory research
by: Lewis, A.
Published: (2018)

Expression of polycomb protein BMI-1 1 maintains the plasticity of basal 2 bronchial epithelial cells
by: Torr, Elizabeth, et al.
Published: (2016)

The use of non-bronchoscopic brushings to study the paediatric airway
by: Lane, C., et al.
Published: (2005)

Chloride intracellular channel 1 (CLIC1) contributes to modulation of cyclic AMP-activated whole cell chloride currents in human bronchial epithelial cells
by: Liu, Bo, et al.
Published: (2018)

Characterisation of human bronchial epithelial response to injury and identification of potential resident progenitor cells in vitro
by: Nijmeh, Hala S.
Published: (2009)

Application of a human primary epithelial-fibroblast co-culture system to study fibrosis
by: Richardson, Jaineeta
Published: (2017)

Successful establishment of primary small airway cell cultures in human lung transplantation
by: Banerjee, B., et al.
Published: (2009)

Novel insight into uPAR function in the bronchial epithelium in asthma using functional genomics
by: Bhaker, Sangita
Published: (2017)

In Vitro primary human airway epithelial whole exhaust exposure
by: Landwehr, Katherine R., et al.
Published: (2021)

Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipients
by: Ling, K.M., et al.
Published: (2019)

Development of a stable T7 RNA polymerase expressing cell line using a lentivirus system
by: Yeong, Ming Yue
Published: (2019)

Developing platforms for tissue engineering of the airways
by: Ramis, Jopeth
Published: (2020)

Characterisation of ATP-binding cassette (ABC) transporters in bronchial epithelial cell culture models
by: Hutter, Victoria
Published: (2012)

Molecular mechanisms of enhanced expression of the chemokine interleukin 8 (CXCL8) in cystic fibrosis (CF) airway epithelial cells
by: Poghosyan, Anna
Published: (2014)

A Comparison of Continuum and Cell-based Models of Colorectal Cancer
by: Walter, Alexander
Published: (2009)

Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells
by: Sidney, Laura E., et al.
Published: (2015)

Developing a chemically defined, xeno-free platform to differentiate human induced pluripotent stem cells to type 2 alveolar epithelial cells of the lung
by: Reed, Liam
Published: (2024)

Development and characterisation of optogenetic tools for non-invasive control of cellular functions in epithelia
by: Ciampani, Victoria
Published: (2019)

Effects of synthetic 2, 4, 6-trihydroxy-3-geranylacetophenone upon TNF-α-induced epithelial dysfunction
by: Sim, Tee Yee
Published: (2016)

Nephronectin and the genetics of lung function variability
by: Qian, Guoqing
Published: (2023)

The role and regulation of the urokinase receptor in asthma and COPD
by: Portelli, Michael A.
Published: (2013)

A genome-wide regulatory network of INTS12 associated with pulmonary function
by: Kheirallah, Alexander K.
Published: (2017)

Expression and regulation of immune-modulatory enzyme Indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation
by: Aldajani, Wejdan A., et al.
Published: (2016)

Limbal stem cells: The search for a marker
by: Chee, K.Y.H., et al.
Published: (2006)

Characterising the structural, functional and metabolomic changes occurring in human corneal cells due to Acanthamoeba castellanii secretome and amelioration of infection using cerium oxide nanoparticles
by: Alhazmi, Abdullah
Published: (2022)

Improved orthotopic and metastatic breast cancer models incorporating key elements of the tumour microenvironment enabling patient-relevant drug testing
by: Nicolaou, Niovi
Published: (2015)

The effects of endocannabinoids and phytocannabinoids on bronchial epithelial permeability
by: Shang, Valerie C.M.
Published: (2016)

Understanding the roles and impact of Solute Carrier Transporters OCT1, OCTN1, and OCTN2 in lung epithelia
by: Magana Gomez, Paulyna Gabriela
Published: (2024)

Effect of Bcl-2 overexpression on cell cycle and antibody productivity in chemostat cultures of myeloma NS0 cells
by: Tey, Beng Ti, et al.
Published: (2005)

Uptake and transport of B12-conjugated nanoparticles in airway epithelium
by: Fowler, Robyn, et al.
Published: (2013)

Triterpene Production in Centella Asiatica (L.) Urban (Pegaga) Callus and Cell Suspension Cultures
by: Ling, Anna Pick Kiong
Published: (2004)

A novel electrospun biphasic scaffold provides optimal three-dimensional topography forin vitroco-culture of airway epithelial and fibroblast cells
by: Morris, G.E., et al.
Published: (2014)

Bat lung epithelial cells show greater host species-specific innate resistance than MDCK cells to human and avian influenza viruses
by: Slater, Tessa, et al.
Published: (2018)

Physical activity in a large sample of adults with intellectual disabilities
by: Barnes, T., et al.
Published: (2013)

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss
by: Chernyavsky, Igor L., et al.
Published: (2018)

Human rather than mouse mesenchymal stem cells in 3D co-culture models boost proliferative and migratory characteristics of colorectal cancer cells through paracrine signalling pathways, highlighting species disconnects
by: Lu, M.
Published: (2022)

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
by: Sampaziotis, Fotios, et al.
Published: (2017)

Review on current issue of clonal banana (Musa sp.) for yield improvement / Noor Maisarah Mohd Noor
by: Mohd Noor, Noor Maisarah
Published: (2017)

Toxicity of different biodiesel exhausts in primary human airway epithelial cells grown at air-liquid interface
by: Landwehr, K.R., et al.
Published: (2022)

Development of collagen functionalized thermally responsive poly(N-isopropylacrylamide) electrospun nanofibers scaffold potentially as a 3D cell culture platform for rat amniotic fluid stem cells
by: Yong, Hsin Nam Ernest
Published: (2023)