Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke

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Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke

Background: Cooling may reduce infarct size and improve neurological outcomes in patients with ischaemic stroke. In phase II trials, cooling awake patients with ischaemic stroke has been shown to be feasible and safe, but the effects in functional outcomes has not yet been investigated in an adequat...

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Bibliographic Details
Main Authors:	Winkel, Per, Bath, Philip M.W., Gluud, Christian, Lindschou, Jane, van der Worp, H. Bart, Macleod, Malcolm R., Szabo, Istvan, Durand-Zaleski, Isabelle, Schwab, Stefan
Format:	Article
Published:	BioMed Central 2017
Subjects:	Acute ischaemic stroke – Randomised clinical trial – Modified Ranking scale – Quality of life – Cooling – Cost-effectiveness
Online Access:	https://eprints.nottingham.ac.uk/49243/

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