Development of novel fluorescent histamine H₁-receptor
antagonists to study ligand-binding kinetics in living cells

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Development of novel fluorescent histamine H₁-receptor antagonists to study ligand-binding kinetics in living cells

The histamine H1-receptor (H1R) is an important mediator of allergy and inflammation. H1R antagonists have particular clinical utility in allergic rhinitis and urticaria. Here we have developed six novel fluorescent probes for this receptor that are very effective for high resolution confocal imagin...

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Bibliographic Details
Main Authors:	Stoddart, Leigh A., Vernall, Andrea J., Bouzo-Lorenzo, Monica, Bosma, Reggie, Kooistra, Albert J., de Graaf, Chris, Vischer, Henry F., Leurs, Rob, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Format:	Article
Published:	Nature Publishing Group 2018
Online Access:	https://eprints.nottingham.ac.uk/49204/

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