Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation

QR Code

Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation

The ability of materials to define the architecture and micro-environment experienced by cells provides new opportunities to direct the fate of human pluripotent stem cells (HPSCs) (Robinton DA, et al (2012) Nature 81:295-305). However, the conditions required for self-renewal verses differentiation...

Full description

Bibliographic Details
Main Authors:	Dixon, James E., Shah, Disheet A., Rogers, Catherine, Hall, Stephen, Weston, Nicola, Parmenter, Christopher D. J., McNally, Donal, Denning, Chris, Shakesheff, Kevin M.
Format:	Article
Language:	English
Published:	National Academy of Sciences 2014
Subjects:	Human Embryonic Stem Cells Differentiation Hydrogel Cardiomyocyte
Online Access:	https://eprints.nottingham.ac.uk/49049/

Similar Items

Current status of drug screening and disease modelling in human pluripotent stem cells
by: Rajamohan, Divya, et al.
Published: (2013)

Improving the mesodermal differentiation potential of human embryonic stem cells
by: Burridge, Paul Wesley
Published: (2008)

Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies?
by: Kalra, Spandan, et al.
Published: (2016)

Evaluating human induced pluripotent stem cell-derived cardiomyocytes for commercial drug testing
by: Katili, Puspita Anggraini
Published: (2020)

Extracellular matrix-derived hydrogels for dental stem cell delivery
by: Viswanath, Aiswarya, et al.
Published: (2016)

Generation and Characterisation of Mesenchymal Stem Cells Derived from Placenta and Adult Cardiac Tissue
by: Vellasamy, Shalini
Published: (2011)

Automation and scale-up of human induced pluripotent stem cell models of cardiovascular disease for drug screening
by: Crutchley, James E.B.
Published: (2016)

Using human induced pluripotent stem cells to study the in vitro phenotype of the cardiac channelopathies
by: Duncan, Gary
Published: (2017)

Establishment of conditional Wnt5a transgenic embryonic stem cell line and its application during neural differentiation process
by: Mohamed Hisham, Nurul Afiqah
Published: (2017)

Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells
by: Kondrashov, Alexander, et al.
Published: (2018)

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
by: Sampaziotis, Fotios, et al.
Published: (2017)

Defining and manipulating the epigenetic stability of human embryonic stem cells
by: Kim, Kee-Pyo
Published: (2009)

Probing E-cadherin Targeting Peptides Using Atomic Force Microscopy
by: Studd, Adam
Published: (2022)

Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
by: Denning, Chris, et al.
Published: (2016)

Discovery of a novel polymer for human pluripotent stem cell expansion and multilineage differentiation
by: Celiz, Adam D., et al.
Published: (2015)

Engineered human pluripotent stem cell derived cardiomyocyte platforms to detect cardiovascular safety liabilities
by: Firth, Karl
Published: (2017)

Developing an automation-compatible quantitative and functional assay for the assessment of pluripotency
by: Flatt, Luke
Published: (2017)

A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays
by: Patel, Asha K., et al.
Published: (2015)

DNA methylation analysis of Sox2 regulatory regions SRR1 and SRR2 in undifferentiated and differentiated mouse embryonic stem cells
by: Batool, Sajida
Published: (2013)

Screening for potential embryotoxicity of phytochemicals and gestational diabetes mellitus using the chick cardiomyocyte micromass system and stem cell differentiation: prediction by molecular targets
by: Mohammed, Omar Jasim Mohammed
Published: (2017)

Investigating stem cell interactions using Atomic force microscopy
by: Graumuller, Friedrich
Published: (2019)

Modulation of lipidomic markers in oxidative stress neural-derived embryonic stem cell cultures with vitamin E supplementation
by: Abd Jalil, Afifah
Published: (2017)

Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning
by: Lim, Sheng Jye, et al.
Published: (2016)

Applications of Raman micro-spectroscopy to stem cell technology: label-free molecular discrimination and monitoring cell differentiation.
by: Ghita, Adrian, et al.
Published: (2015)

Gradient delivery of bioactive molecules across porous hydrogels
by: Eltaher, Hoda M.M.A.
Published: (2016)

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy
by: Mosqueira, Diogo, et al.
Published: (2018)

Combining extracellular matrix hydrogels and electrical stimulation to influence macrophage polarisation
by: Whitehead, Charlie D.
Published: (2024)

Human pluripotent stem cells derived-cardiomyocytes (hPSC-CMs) to assess the impact of drug- and gene-induced changes on cell function
by: Mohd Yusof, Nurul Ain Nasim
Published: (2020)

MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo
by: Sala, L., et al.
Published: (2017)

Evaluation of minicircle-induced pluripotent stem cell
by: Daneshvar, Nasibeh
Published: (2014)

Differentiation of embryonic stem cells through controlled release of growth factors from microspheres
by: olaye, eghosa omoregie andrew/ E A O
Published: (2009)

Bio-responsive hydrogels for an in vitro brain cancer cell model: self-controlled inhibition of matrix metalloproteinase activity
by: Russo, Emanuele
Published: (2020)

Development of a human induced pluripotent stem cells (hiPSCs)-derived, universal platform, for generation of immunocompetent multi-tissue organoids
by: Azis, Rizal
Published: (2024)

Disease modeling hypertrophic cardiomyopathy using CRISPR/Cas9 genome editing technology in human pluripotent stem cell-derived cardiomyocytes
by: Mosqueira, Diogo
Published: (2018)

Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration
by: Paduano, Francesco, et al.
Published: (2017)

Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology
by: Lei, Chon-Lok, et al.
Published: (2017)

To F-SIMS/XPS chemical depth profiling of synthetic polymer hydrogels
by: Taylor, Michael
Published: (2017)

Generation of mouse induced pluripotent stem cells using polycistronic lentiviral vector in feeder - and serum-free culture
by: Mahmaud, Akram Faisal
Published: (2015)

Development of biomaterial applications for the investigation of the influence of dynamic mechanical cues and matrix apparent stiffness on the behaviour of contractile cells
by: Encerrado Flores, Ana L.
Published: (2022)

User-defined biomimetic scaffolds through "click" modification of self-assembling peptide hydrogels
by: Merrett, Christopher G.
Published: (2024)