Using chromosome engineering on a natural isolate of the fission yeast, Schizosaccharomyces pombe, to investigate the epigenetic inheritance of the kinetochore

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Using chromosome engineering on a natural isolate of the fission yeast, Schizosaccharomyces pombe, to investigate the epigenetic inheritance of the kinetochore

In many eukaryotes, kinetochores may form over a variety of unrelated centromeric sequences. This fact has led to the idea that an epigenetic process determines kinetochore location. To investigate the nature of this epigenetic process, I have established a system that allows the manipulation of th...

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Bibliographic Details
Main Author:	Barbosa, Anne Caroline
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	Centromere kinetochore Cenp-A epigenetic inheritance Schizosaccharomyces pombe genetic engineering recombinases
Online Access:	https://eprints.nottingham.ac.uk/49006/

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