Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis
Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented. Such registers are integral to the process of scientific reviewing. We document and discuss met...
| Main Authors: | , |
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| Format: | Article |
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Tabriz University of Medical Sciences
2017
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| Online Access: | https://eprints.nottingham.ac.uk/48979/ |
| _version_ | 1848797894109298688 |
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| author | Shokraneh, Farhad Adams, Clive E. |
| author_facet | Shokraneh, Farhad Adams, Clive E. |
| author_sort | Shokraneh, Farhad |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented. Such registers are integral to the process of scientific reviewing. We document and discuss methodological aspects of the development and use of study-based registers. Although the content is focused on the study-based register of randomized/controlled clinical trials, this work applies to developers of databases of all sorts of studies related to the human, animals, cells, genes, and molecules.
Methods: We describe necessity, rationale, and steps for the development, utilization and maintenance of study-based registers as well as the challenges and gains for the organizations supporting systematic reviews of the published and unpublished literature.
Conclusion: The ultimate goal of having a study-based register is to facilitate efficient production of systematic reviews providing rapid, yet accurate, evidence for the decision-makers. We argue that moving towards study-based registers is an inevitable welcome direction and that infrastructures are ready for such movement. |
| first_indexed | 2025-11-14T20:11:07Z |
| format | Article |
| id | nottingham-48979 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:11:07Z |
| publishDate | 2017 |
| publisher | Tabriz University of Medical Sciences |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-489792020-05-04T19:12:41Z https://eprints.nottingham.ac.uk/48979/ Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis Shokraneh, Farhad Adams, Clive E. Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented. Such registers are integral to the process of scientific reviewing. We document and discuss methodological aspects of the development and use of study-based registers. Although the content is focused on the study-based register of randomized/controlled clinical trials, this work applies to developers of databases of all sorts of studies related to the human, animals, cells, genes, and molecules. Methods: We describe necessity, rationale, and steps for the development, utilization and maintenance of study-based registers as well as the challenges and gains for the organizations supporting systematic reviews of the published and unpublished literature. Conclusion: The ultimate goal of having a study-based register is to facilitate efficient production of systematic reviews providing rapid, yet accurate, evidence for the decision-makers. We argue that moving towards study-based registers is an inevitable welcome direction and that infrastructures are ready for such movement. Tabriz University of Medical Sciences 2017-10-15 Article PeerReviewed Shokraneh, Farhad and Adams, Clive E. (2017) Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis. Bioimpacts, 7 (4). pp. 209-217. ISSN 2228-5652 http://bi.tbzmed.ac.ir/Abstract/bi-17429 doi:10.15171/bi.2017.25 doi:10.15171/bi.2017.25 |
| spellingShingle | Shokraneh, Farhad Adams, Clive E. Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis |
| title | Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis |
| title_full | Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis |
| title_fullStr | Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis |
| title_full_unstemmed | Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis |
| title_short | Study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis |
| title_sort | study-based registers of randomized controlled trials: starting a systematic review with data extraction or meta-analysis |
| url | https://eprints.nottingham.ac.uk/48979/ https://eprints.nottingham.ac.uk/48979/ https://eprints.nottingham.ac.uk/48979/ |