Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial

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Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial

Objectives: To test whether administration of the antifibrinolytic drug tranexamic acid (TXA) in patients with spontaneous intracerebral haemorrhage (SICH) leads to increased prevalence of diffusion-weighted MRI defined hyperintense ischaemic lesions (primary hypothesis) or reduced perihaematomal oe...

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Bibliographic Details
Main Authors:	Dineen, Robert A., Pszczolkowski, Stefan, Flaherty, Katie, Law, Zhe Kang, Morgan, Paul S., Roberts, Ian, Werring, David, Al-Shahi Salman, Rustam, England, Timothy J., Bath, Philip M.W., Sprigg, Nikola
Format:	Article
Published:	BMJ Publishing Group Ltd 2018
Subjects:	hyperacute primary intracerebral haemorrhage; tranexamic acid; magnetic resonance imaging; diffusion weighted imaging; perihaematomal oedema
Online Access:	https://eprints.nottingham.ac.uk/48960/

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