A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells
Dormant leukaemia initiating cells in the bone marrow niche are a crucial therapeutic target for total eradication of acute myeloid leukaemia. To study this cellular subset we created and validated an in vitro model employing the cell line TF-1a, treated with Transforming Growth Factor β1 (TGFβ1) an...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Published: |
Impact Journals
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/48721/ |