Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat
A 12-year-old domestic shorthair cat was presented with acute non-painful hindlimb proprioceptive ataxia localising to T3–L3 spinal cord segments. MRI revealed paravertebral muscular hyperintensity on T2-weighted images at the level of T7–T8 vertebrae. The cat improved on conservative management but...
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| Format: | Article |
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SAGE Publications
2017
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| Online Access: | https://eprints.nottingham.ac.uk/48651/ |
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| author | Posporis, Christoforos Grau-Roma, Llorenc Travetti, Olga Oliveira, Maria Polledo, Laura Wessmann, Annette |
| author_facet | Posporis, Christoforos Grau-Roma, Llorenc Travetti, Olga Oliveira, Maria Polledo, Laura Wessmann, Annette |
| author_sort | Posporis, Christoforos |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | A 12-year-old domestic shorthair cat was presented with acute non-painful hindlimb proprioceptive ataxia localising to T3–L3 spinal cord segments. MRI revealed paravertebral muscular hyperintensity on T2-weighted images at the level of T7–T8 vertebrae. The cat improved on conservative management but deteriorated 3 months later. Repeated MRI showed meningeal enhancement at the same level and hyperintensity of the paravertebral musculature extending to the right thoracic wall and pleural space on short tau inversion recovery images. Thoracic CT showed mineralised lesions of the right lung, restricted pleural effusion and expansile bone lesions affecting multiple ribs. The cat had been treated for pyothorax 5 years earlier but manifested no current respiratory signs. Cerebrospinal fluid (CSF) examination showed lymphocytic pleocytosis but no neoplastic cells. Biopsy of the affected muscles and cytology of the lung and pleural lesions suggested a malignant epithelial cell tumour. Post-mortem examination confirmed a pulmonary adenocarcinoma locally infiltrating the thoracic wall, T7–T8 vertebrae and the spinal cord white matter. Meningeal carcinomatosis was detected with neoplastic cells invading the ventral median fissure of the spinal cord. No metastases were observed in other organs, indicating that neoplastic cells reached the spinal cord by direct extension. |
| first_indexed | 2025-11-14T20:09:52Z |
| format | Article |
| id | nottingham-48651 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:09:52Z |
| publishDate | 2017 |
| publisher | SAGE Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-486512020-05-04T18:52:53Z https://eprints.nottingham.ac.uk/48651/ Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat Posporis, Christoforos Grau-Roma, Llorenc Travetti, Olga Oliveira, Maria Polledo, Laura Wessmann, Annette A 12-year-old domestic shorthair cat was presented with acute non-painful hindlimb proprioceptive ataxia localising to T3–L3 spinal cord segments. MRI revealed paravertebral muscular hyperintensity on T2-weighted images at the level of T7–T8 vertebrae. The cat improved on conservative management but deteriorated 3 months later. Repeated MRI showed meningeal enhancement at the same level and hyperintensity of the paravertebral musculature extending to the right thoracic wall and pleural space on short tau inversion recovery images. Thoracic CT showed mineralised lesions of the right lung, restricted pleural effusion and expansile bone lesions affecting multiple ribs. The cat had been treated for pyothorax 5 years earlier but manifested no current respiratory signs. Cerebrospinal fluid (CSF) examination showed lymphocytic pleocytosis but no neoplastic cells. Biopsy of the affected muscles and cytology of the lung and pleural lesions suggested a malignant epithelial cell tumour. Post-mortem examination confirmed a pulmonary adenocarcinoma locally infiltrating the thoracic wall, T7–T8 vertebrae and the spinal cord white matter. Meningeal carcinomatosis was detected with neoplastic cells invading the ventral median fissure of the spinal cord. No metastases were observed in other organs, indicating that neoplastic cells reached the spinal cord by direct extension. SAGE Publications 2017-07-01 Article PeerReviewed Posporis, Christoforos, Grau-Roma, Llorenc, Travetti, Olga, Oliveira, Maria, Polledo, Laura and Wessmann, Annette (2017) Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat. Journal of Feline Medicine and Surgery Open Reports, 3 (2). pp. 1-6. ISSN 2055-1169 https://doi.org/10.1177/2055116917742812 doi:10.1177/2055116917742812 doi:10.1177/2055116917742812 |
| spellingShingle | Posporis, Christoforos Grau-Roma, Llorenc Travetti, Olga Oliveira, Maria Polledo, Laura Wessmann, Annette Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat |
| title | Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat |
| title_full | Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat |
| title_fullStr | Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat |
| title_full_unstemmed | Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat |
| title_short | Meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat |
| title_sort | meningeal carcinomatosis and spinal cord infiltration caused by a locally invasive pulmonary adenocarcinoma in a cat |
| url | https://eprints.nottingham.ac.uk/48651/ https://eprints.nottingham.ac.uk/48651/ https://eprints.nottingham.ac.uk/48651/ |