Water contact angle is not a good predictor of biological responses to materials
Often the view is expressed that water contact angle (WCA) or other wettability/surface energy measurements made on a material surface can be used to predict cellular attachment to materials, e.g., bacteria attach to hydrophobic surfaces. In this article, the authors present a perspective emerging f...
| Main Authors: | , |
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| Format: | Article |
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AIP Publishing
2017
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| Online Access: | https://eprints.nottingham.ac.uk/48589/ |
| _version_ | 1848797800908718080 |
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| author | Alexander, Morgan R. Williams, Paul |
| author_facet | Alexander, Morgan R. Williams, Paul |
| author_sort | Alexander, Morgan R. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Often the view is expressed that water contact angle (WCA) or other wettability/surface energy measurements made on a material surface can be used to predict cellular attachment to materials, e.g., bacteria attach to hydrophobic surfaces. In this article, the authors present a perspective emerging from their work that has failed to find relationships between WCA and microbial and stem cell attachment within large diversity material libraries and compare with the literature concluding that such simple rules are (unfortunately) wholly inadequate to explain cell–material interactions. |
| first_indexed | 2025-11-14T20:09:38Z |
| format | Article |
| id | nottingham-48589 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:09:38Z |
| publishDate | 2017 |
| publisher | AIP Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-485892020-05-04T18:54:35Z https://eprints.nottingham.ac.uk/48589/ Water contact angle is not a good predictor of biological responses to materials Alexander, Morgan R. Williams, Paul Often the view is expressed that water contact angle (WCA) or other wettability/surface energy measurements made on a material surface can be used to predict cellular attachment to materials, e.g., bacteria attach to hydrophobic surfaces. In this article, the authors present a perspective emerging from their work that has failed to find relationships between WCA and microbial and stem cell attachment within large diversity material libraries and compare with the literature concluding that such simple rules are (unfortunately) wholly inadequate to explain cell–material interactions. AIP Publishing 2017-07-06 Article PeerReviewed Alexander, Morgan R. and Williams, Paul (2017) Water contact angle is not a good predictor of biological responses to materials. Biointerphases, 12 (2). 02C201. ISSN 1934-8630 http://avs.scitation.org/doi/abs/10.1116/1.4989843 doi:10.1116/1.4989843 doi:10.1116/1.4989843 |
| spellingShingle | Alexander, Morgan R. Williams, Paul Water contact angle is not a good predictor of biological responses to materials |
| title | Water contact angle is not a good predictor of biological responses to materials |
| title_full | Water contact angle is not a good predictor of biological responses to materials |
| title_fullStr | Water contact angle is not a good predictor of biological responses to materials |
| title_full_unstemmed | Water contact angle is not a good predictor of biological responses to materials |
| title_short | Water contact angle is not a good predictor of biological responses to materials |
| title_sort | water contact angle is not a good predictor of biological responses to materials |
| url | https://eprints.nottingham.ac.uk/48589/ https://eprints.nottingham.ac.uk/48589/ https://eprints.nottingham.ac.uk/48589/ |