A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells

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A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells

Recent advances in fluorescent ligand technology have enabled the study of G protein-coupled receptors in their native environment without the need for genetic modification such as addition of N-terminal fluorescent or bioluminescent tags. Here, we have used a non-imaging plate reader (PHERAstar FS)...

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Bibliographic Details
Main Authors:	Arruda, Maria Augusta, Stoddart, Leigh A., Gherbi, Karolina, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Format:	Article
Published:	Frontiers 2017
Subjects:	adenosine receptors fluorescent ligands Adenosine A3 receptor High throughput screening LOPAC library
Online Access:	https://eprints.nottingham.ac.uk/48473/

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