Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis
Drug selection of rapid acting fentanyl formulations in the treatment of breakthrough pain in patients with cancer is performed by the System of Objectified Judgement Analysis method. All seven available formulations were included in the analysis. The following selection criteria were used: number o...
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| Format: | Article |
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BMJ Publishing Group
2017
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| Online Access: | https://eprints.nottingham.ac.uk/48457/ |
| _version_ | 1848797767978188800 |
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| author | Janknegt, Robert van den Beuken, Marieke Schiere, Sjouke Überall, Michael Knaggs, Roger Hanley, Jaquie Thronaes, Morten |
| author_facet | Janknegt, Robert van den Beuken, Marieke Schiere, Sjouke Überall, Michael Knaggs, Roger Hanley, Jaquie Thronaes, Morten |
| author_sort | Janknegt, Robert |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Drug selection of rapid acting fentanyl formulations in the treatment of breakthrough pain in patients with cancer is performed by the System of Objectified Judgement Analysis method. All seven available formulations were included in the analysis. The following selection criteria were used: number of available strengths, variability in the rate of absorption, interactions, clinical efficacy, side effects, ease of administration and documentation. No direct double-blind comparative studies between two or more formulations were identified and the clinical documentation of all formulations is limited. The most distinguishing criterion was ease of use. This led to slightly higher scores for Abstral, Instanyl and PecFent than for the other formulations. The pros and cons of each formulation should be discussed with the patient, and the most suitable formulation selected for each individual patient. |
| first_indexed | 2025-11-14T20:09:07Z |
| format | Article |
| id | nottingham-48457 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:09:07Z |
| publishDate | 2017 |
| publisher | BMJ Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-484572020-05-04T18:31:02Z https://eprints.nottingham.ac.uk/48457/ Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis Janknegt, Robert van den Beuken, Marieke Schiere, Sjouke Überall, Michael Knaggs, Roger Hanley, Jaquie Thronaes, Morten Drug selection of rapid acting fentanyl formulations in the treatment of breakthrough pain in patients with cancer is performed by the System of Objectified Judgement Analysis method. All seven available formulations were included in the analysis. The following selection criteria were used: number of available strengths, variability in the rate of absorption, interactions, clinical efficacy, side effects, ease of administration and documentation. No direct double-blind comparative studies between two or more formulations were identified and the clinical documentation of all formulations is limited. The most distinguishing criterion was ease of use. This led to slightly higher scores for Abstral, Instanyl and PecFent than for the other formulations. The pros and cons of each formulation should be discussed with the patient, and the most suitable formulation selected for each individual patient. BMJ Publishing Group 2017-01-11 Article PeerReviewed Janknegt, Robert, van den Beuken, Marieke, Schiere, Sjouke, Überall, Michael, Knaggs, Roger, Hanley, Jaquie and Thronaes, Morten (2017) Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis. European Journal of Hospital Pharmacy . ISSN 2047-9964 http://ejhp.bmj.com/content/early/2017/01/11/ejhpharm-2016-001127 doi:10.1136/ejhpharm-2016-001127 doi:10.1136/ejhpharm-2016-001127 |
| spellingShingle | Janknegt, Robert van den Beuken, Marieke Schiere, Sjouke Überall, Michael Knaggs, Roger Hanley, Jaquie Thronaes, Morten Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis |
| title | Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis |
| title_full | Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis |
| title_fullStr | Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis |
| title_full_unstemmed | Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis |
| title_short | Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis |
| title_sort | rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the system of objectified judgement analysis |
| url | https://eprints.nottingham.ac.uk/48457/ https://eprints.nottingham.ac.uk/48457/ https://eprints.nottingham.ac.uk/48457/ |