Improving readiness for recruitment through simulated trial activation: the Adjuvant Steroids in Adults with Pandemic
influenza (ASAP) trial

QR Code

Improving readiness for recruitment through simulated trial activation: the Adjuvant Steroids in Adults with Pandemic influenza (ASAP) trial

Background: Research in public health emergencies requires trials to be set up in readiness for activation at short notice and in anticipation of limited timelines for patient recruitment. We conducted a simulated activation of a hibernating pandemic influenza clinical trial in order to test trial p...

Full description

Bibliographic Details
Main Authors:	Lim, Wei Shen, Meakin, Garry, Brittain, Claire, Bewick, Thomas, Duley, Lelia
Format:	Article
Published:	BioMed Central 2017
Subjects:	Pandemic Influenza Clinical trial Simulation Hibernation Corticosteroids Delay Trial delivery
Online Access:	https://eprints.nottingham.ac.uk/48454/

Similar Items

Effect of corticosteroid therapy on influenza-related mortality: a systematic review and meta-analysis
by: Rodrigo, Chamira, et al.
Published: (2015)

Home interventions and light therapy for treatment of vitiligo (HI-Light Vitiligo Trial): study protocol for a randomized controlled trial
by: Haines, Rachel H., et al.
Published: (2018)

FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations
by: Skeggs, Andrew, et al.
Published: (2016)

Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial
by: Brittain, Claire, et al.
Published: (2016)

Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial
by: Brittain, Claire, et al.
Published: (2016)

Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation
by: Lim, Wei Shen, et al.
Published: (2015)

Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
by: Nyland, G.A., et al.
Published: (2014)

How clinically relevant are treatment comparisons of topical calcineurin inhibitor trials for atopic eczema?
by: Wilkes, Sally R., et al.
Published: (2016)

Early experience with influenza A H1N109 in an Australian intensive care unit
by: Leen, T., et al.
Published: (2010)

Guidelines for reporting embedded recruitment trials
by: Madurasinghe, Vichithranie W., et al.
Published: (2016)

Factors affecting recruitment to breast cancer clinical trials: an examination of the British Association of Surgical Oncology II trial and the International Breast Cancer Intervention Study
by: Maslin-Prothero, Sian
Published: (2000)

Care in HIV drug trial closure: perspectives of research participants and staff in Uganda
by: Nalubega, Sylivia
Published: (2017)

Women’s views and experiences of two alternative consent pathways for participation in a preterm intrapartum trial: a qualitative study
by: Sawyer, Alexandra, et al.
Published: (2017)

Clinicians' attitude towards a placebo-controlled randomised clinical trial investigating the effect of neuraminidase inhibitors in adults hospitalised with influenza
by: Bradbury, Naomi, et al.
Published: (2018)

Clinicans' views and experiences of two alternative consent pathways for participation in a preterm intrapartum trial: a qualitative study
by: Chhoa, Celine Y., et al.
Published: (2017)

An international study of the use of pandemic vaccines during the 2009-10 influenza A(H1N1) pandemic: a qualitative methodological study
by: Pinder, Leila
Published: (2017)

Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials
by: Woodhouse, Lisa Jane
Published: (2022)

Systematic overview of clinical trials of antiarrhythmic drugs
by: Shilbayeh, Sirin
Published: (1998)

Ethics of planning for, and responding to, pandemic influenza in Sub Saharan Africa: qualitative study
by: Sambala, Evanson Zondani
Published: (2014)

Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies
by: Okoli, G.N., et al.
Published: (2014)

Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial
by: Anderson, J.R., et al.
Published: (2016)

Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials
by: Bath, Philip
Published: (2007)

Can we improve the statistical analysis of stroke trials? Statistical re-analysis of functional outcomes in stroke trials
by: Bath, Philip M.W.
Published: (2007)

Cord pilot trial - immediate versus deferred cord clamping for very preterm birth (before 32 weeks gestation): study protocol for a randomized controlled trial
by: Pushpa-Rajah, Angela, et al.
Published: (2014)

Delayed publications of clinical trials in cystic fibrosis
by: Hurley, M.N., et al.
Published: (2011)

The Virtual International Stroke Trials Archive
by: Myzoon, Ali, et al.
Published: (2007)

Registration and outcome reporting bias in randomised controlled trials of distal radius fracture treatment: a systematic review
by: Lee, Sheila, et al.
Published: (2018)

Adjudicating outcomes in stroke trials
by: Godolphin, Peter J.
Published: (2019)

Can oral corticosteroids reduce the severity or duration of an acute cough, and the associated National Health Service and societal costs, in adults presenting to primary care?: study protocol for a randomised controlled trial
by: Downing, Harriet E., et al.
Published: (2015)

Australian Aboriginal and Torres Strait Islander communities and the development of pandemic influenza containment strategies: Community voices and community control
by: Massey, P., et al.
Published: (2011)

A pilot randomized controlled trial comparing effectiveness of prism glasses, visual search training and standard care in hemianopia
by: Rowe, Fiona, et al.
Published: (2017)

The conduct of summary trial in military law - practice and procedure / Amir Hamzah Ahmad, Kamarularifin Nordin and Mohd Nasir Abd Aziz
by: Ahmad, Amir Hamzah, et al.
Published: (2005)

Baseline characteristics of the 3,096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial
by: Bath, Philip M.W., et al.
Published: (2017)

Effect of Early Secreted Antigen Target-6 Gene of Mycobacterium Tuberculosis as Genetic Adjuvant for Avian Influenza Virus DNA Vaccine in Chickens
by: Oveissi, Sara
Published: (2009)

Revisiting the law regarding sentences of kidnapping in Malaysia: an analysis / Nurul Farhana Adnan, Afaf Abdul Rahman and Siti Ridha Fateha Razali
by: Adnan, Nurul Farhana, et al.
Published: (2014)

Investigating the effect of independent blinded digital image assessment on the STOP GAP trial
by: Patsko, Emily, et al.
Published: (2017)

A randomised controlled trial of the clinical effectiveness and cost-effectiveness of the levonorgestrel-releasing intrauterine system in primary care against standard treatment for menorrhagia: the ECLIPSE trial
by: Gupta, Janesh K., et al.
Published: (2015)

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
by: Sprigg, Nikola, et al.
Published: (2018)

Randomised trial of cord clamping and initial stabilisation at very preterm birth
by: Duley, Lelia, et al.
Published: (2017)

Anticipated regret and organ donor registration: a randomised controlled trial
by: O'Carroll, Ronan E., et al.
Published: (2016)