Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1

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Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1

Monoclonal antibodies (mAbs) targeting the hepatitis C virus (HCV) envelope have been raised mainly against envelope protein 2 (E2), while the antigenic epitopes of envelope protein 1 (E1) are not fully identified. Here we describe the detailed characterization of a human mAb, designated A6, generat...

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Bibliographic Details
Main Authors:	Mesalam, Ahmed Atef, Desombere, Isabelle, Farhoudi, Ali, Van Houtte, Freya, Verhoye, Lieven, Ball, Jonathan, Dubuisson, Jean, Foung, Steven K.H., Patel, Arvind H., Persson, Mats A.A., Leroux-Roels, Geert, Meuleman, Philip
Format:	Article
Published:	Elsevier 2018
Subjects:	Hepatitis C virus; Envelope protein; Antibody; Entry; Vaccine
Online Access:	https://eprints.nottingham.ac.uk/48359/

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