A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

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A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

Infections with hepatitis C virus (HCV) represent a worldwide health burden and a prophylactic vaccine is still not available. Liver transplantation (LT) is often the only option for patients with HCV-induced end-stage liver disease. However, immediately after transplantation, the liver graft become...

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Bibliographic Details
Main Authors:	Desombere, Isabelle, Mesalam, Ahmed Atef, Urbanowicz, Richard A., Van Houtte, Freya, Verhoye, Lieven, Keck, Zhen-Yong, Farhoudi, Ali, Vercauteren, Koen, Weening, Karin E., Baumert, Thomas F., Patel, Arvind H., Foung, Steven K.H., Ball, Jonathan, Leroux-Roels, Geert, Meuleman, Philip
Format:	Article
Published:	Elsevier 2017
Subjects:	Hepatitis C virus; envelope protein; neutralizing antibody; chimeric mice; liver transplantation; vaccine
Online Access:	https://eprints.nottingham.ac.uk/48357/

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