Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial

Background Innovative strategies are required to improve access to evidence-based tinnitus interventions. A guided Internet-based cognitive behavioural therapy (iCBT) intervention for tinnitus was therefore developed for a U.K. population. Initial clinical trials indicated efficacy of iCBT at red...

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Main Authors: Beukes, Eldre W., Baguley, David, Allen, Peter M., Manchaiah, Vinaya, Andersson, Gerhard
Format: Article
Published: BioMed Central 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/48199/
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author Beukes, Eldre W.
Baguley, David
Allen, Peter M.
Manchaiah, Vinaya
Andersson, Gerhard
author_facet Beukes, Eldre W.
Baguley, David
Allen, Peter M.
Manchaiah, Vinaya
Andersson, Gerhard
author_sort Beukes, Eldre W.
building Nottingham Research Data Repository
collection Online Access
description Background Innovative strategies are required to improve access to evidence-based tinnitus interventions. A guided Internet-based cognitive behavioural therapy (iCBT) intervention for tinnitus was therefore developed for a U.K. population. Initial clinical trials indicated efficacy of iCBT at reducing tinnitus severity and associated comorbidities such as insomnia and depression. The aim of this phase III randomised controlled trial is to compare this new iCBT intervention with an established intervention, namely face-to-face clinical care for tinnitus. Methods/design This will be a multi-centre study undertaken across three hospitals in the East of England. The design is a randomised, two-arm, parallel-group, non-inferiority trial with a 2-month follow-up. The experimental group will receive the guided iCBT intervention, whereas the active control group will receive the usual face-to-face clinical care. An independent researcher will randomly assign participants, using a computer-generated randomisation schedule, after stratification for tinnitus severity. There will be 46 participants in each group. The primary assessment measure will be the Tinnitus Functional Index. Data analysis will establish whether non-inferiority is achieved using a pre-defined non-inferiority margin. Discussion This protocol outlines phase III of a clinical trial comparing a new iCBT with established face-to-face care for tinnitus. If guided iCBT for tinnitus proves to be as effective as the usual tinnitus care, it may be a viable additional management route for individuals with tinnitus. This could increase access to evidence-based effective tinnitus care and reduce the pressures on existing health care systems.
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spelling nottingham-481992020-05-04T18:42:48Z https://eprints.nottingham.ac.uk/48199/ Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial Beukes, Eldre W. Baguley, David Allen, Peter M. Manchaiah, Vinaya Andersson, Gerhard Background Innovative strategies are required to improve access to evidence-based tinnitus interventions. A guided Internet-based cognitive behavioural therapy (iCBT) intervention for tinnitus was therefore developed for a U.K. population. Initial clinical trials indicated efficacy of iCBT at reducing tinnitus severity and associated comorbidities such as insomnia and depression. The aim of this phase III randomised controlled trial is to compare this new iCBT intervention with an established intervention, namely face-to-face clinical care for tinnitus. Methods/design This will be a multi-centre study undertaken across three hospitals in the East of England. The design is a randomised, two-arm, parallel-group, non-inferiority trial with a 2-month follow-up. The experimental group will receive the guided iCBT intervention, whereas the active control group will receive the usual face-to-face clinical care. An independent researcher will randomly assign participants, using a computer-generated randomisation schedule, after stratification for tinnitus severity. There will be 46 participants in each group. The primary assessment measure will be the Tinnitus Functional Index. Data analysis will establish whether non-inferiority is achieved using a pre-defined non-inferiority margin. Discussion This protocol outlines phase III of a clinical trial comparing a new iCBT with established face-to-face care for tinnitus. If guided iCBT for tinnitus proves to be as effective as the usual tinnitus care, it may be a viable additional management route for individuals with tinnitus. This could increase access to evidence-based effective tinnitus care and reduce the pressures on existing health care systems. BioMed Central 2017-04-21 Article PeerReviewed Beukes, Eldre W., Baguley, David, Allen, Peter M., Manchaiah, Vinaya and Andersson, Gerhard (2017) Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial. Trials, 18 . 186/1-186/11. ISSN 1745-6215 Service development; Tinnitus management; Clinical intervention; Tinnitus distress; Non-inferiority trial; Tinnitus treatment; Internet intervention; Cognitive behavioural therapy; Guided intervention https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-017-1931-6 doi:10.1186/s13063-017-1931-6 doi:10.1186/s13063-017-1931-6
spellingShingle Service development; Tinnitus management; Clinical intervention; Tinnitus distress; Non-inferiority trial; Tinnitus treatment; Internet intervention; Cognitive behavioural therapy; Guided intervention
Beukes, Eldre W.
Baguley, David
Allen, Peter M.
Manchaiah, Vinaya
Andersson, Gerhard
Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial
title Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial
title_full Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial
title_fullStr Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial
title_full_unstemmed Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial
title_short Guided Internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial
title_sort guided internet-based versus face-to-face clinical care in the management of tinnitus: study protocol for a multi-centre randomised controlled trial
topic Service development; Tinnitus management; Clinical intervention; Tinnitus distress; Non-inferiority trial; Tinnitus treatment; Internet intervention; Cognitive behavioural therapy; Guided intervention
url https://eprints.nottingham.ac.uk/48199/
https://eprints.nottingham.ac.uk/48199/
https://eprints.nottingham.ac.uk/48199/