What is the risk of progressive multifocal leukoencephalopathy in patients with ulcerative colitis or Crohn’s Disease treated with vedolizumab?

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What is the risk of progressive multifocal leukoencephalopathy in patients with ulcerative colitis or Crohn’s Disease treated with vedolizumab?

Background: Progressive multifocal leukoencephalopathy is a serious condition linked to certain diseases and immunosuppressant therapies, including the α4 integrin antagonist natalizumab. No cases have been reported to date with vedolizumab, a selective antagonist of the α4β7 integrin expressed on g...

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Bibliographic Details
Main Authors:	Card, Timothy R., Xu, Jing, Liang, Huifang, Bhayat, Fatima
Format:	Article
Language:	English
Published:	Lippincott, Williams & Wilkins 2018
Subjects:	Epidemiology; Clinical trials; Progressive multifocal leukoencephalopathy; Inflammatory bowel disease; Vedolizumab
Online Access:	https://eprints.nottingham.ac.uk/48172/

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