Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon

QR Code

Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon

Objective: We sought to quantify the anti-inflammatory effects of two cannabinoid drugs, cannabidiol (CBD) and palmitoylethanolamide (PEA), in cultured cell lines and compared this effect with experimentally inflamed explant human colonic tissue. These effects were explored in acutely and chronicall...

Full description

Bibliographic Details
Main Authors:	Couch, Daniel G., Tasker, Chris, Theophilidou, Elena, Lund, Jonathan N., O'Sullivan, Saoirse
Format:	Article
Published:	Portland Press 2017
Online Access:	https://eprints.nottingham.ac.uk/48096/

Similar Items

The actions of cannabidiol and palmitoylethanolamide on inflammation and permeability of the gut
by: Couch, Daniel
Published: (2018)

A systematic review and meta-analysis of the haemodynamic effects of cannabidiol
by: Sultan, Salahaden R., et al.
Published: (2017)

A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study
by: Jadoon, Khalid A., et al.
Published: (2017)

In vivo cannabidiol treatment improves endothelium-dependent vasorelaxation in mesenteric arteries of Zucker diabetic fatty rats
by: Wheal, Amanda J., et al.
Published: (2017)

The use of cannabinoids in colitis: a systematic review and meta-analysis
by: Couch, Daniel G., et al.
Published: (2018)

The role of CB1 in intestinal permeability and inflammation
by: Karwad, Mustafa A., et al.
Published: (2017)

Bidirectional effects of cannabidiol on contextual fear memory extinction
by: Song, Chenchen, et al.
Published: (2016)

Anti-inflammatory, analgesic and acute toxicity effects of fermented soybean
by: Mohd Yusof, Hamidah, et al.
Published: (2019)

Antioxidant, anti-inflammatory and anti-proliferative effects of methanolic leaf extract of Muntingia calabura L. on colon cancer
by: Md Nasir, Nur Liana
Published: (2017)

Cannabidiol regulation of extinction and relapse of learned fear
by: Papagianni, Eleni
Published: (2023)

Anti-inflammatory activity of kapok (ceiba pentandra) thorns in acute inflammation
by: Hashim, Ridzwan, et al.
Published: (2014)

Anti-inflammatory activity of kapok thorn (Ceiba pentandra)in acute inflammation
by: Hashim, Ridzwan, et al.
Published: (2014)

Anti-Inflammatory Cytokines Predominate in Acute Human Plasmodium knowlesi Infections
by: Cox-Singh, J., et al.
Published: (2011)

Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)

Efficacy and safety of Cannabidiol and Tetrahydrocannabivarin on glycemic and lipid parameters in patients with Type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel group pilot study
by: Jadoon, Khalid A., et al.
Published: (2016)

Localisation of citrullinated and carbamylated proteins in the inflamed gingival tissues of rheumatoid arthritis / Lee Yin Hui
by: Lee, Yin Hui
Published: (2019)

Cannabidiol regulation of learned fear: implications for treating anxiety-related disorders
by: Jurkus, Regimantas, et al.
Published: (2016)

CD95-mediated calcium signaling promotes T helper 17 trafficking to inflamed organs in lupus-prone mice
by: Poissonnier, Amanda, et al.
Published: (2016)

Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα
by: Karwad, Mustafa A., et al.
Published: (2016)

Non-invasive colonic imaging studies in inflammatory bowel disease
by: Alshammari, Meshari Turki
Published: (2024)

Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders
by: Lee, Jonathan L.C., et al.
Published: (2017)

Characterisation of the haemodynamic effects of cannabidiol in humans using duplex ultrasound and other techniques
by: Sultan, Salahaden
Published: (2020)

Learned fear extinction: an interdisciplinary investigation of the neurocircuitry and the potential therapeutic benefit of cannabidiol
by: Jurkus, Regimantas
Published: (2019)

Evaluation of fructus viticis methanolic crude extract as antioxidant and anti-inflammatory in carrageenan induced acute paw oedema
by: Azizul, Nurul Husna
Published: (2020)

Manilkara zapota (L.) P. royen leaf mitigates colitis-associated colon cancer through anti-inflammatory modulation in BALB/C Mice
by: Mohd Esa, Norhaizan, et al.
Published: (2024)

Potential anti-inflammatory and anti-cancer properties of farnesol
by: Jung, Y., et al.
Published: (2018)

Development and evaluation of cannabidiol formulations for delivery to the central nervous system to treat neuropathic pain
by: Muresan, Paula Diana
Published: (2022)

Anti-inflammatory activity of centella asiatica
by: Isuparan, Dinishkumari
Published: (2012)

Anti-inflammatory, anti-cholinergic and cytotoxic effects of Sida rhombifolia
by: Mah, Siau Hui, et al.
Published: (2017)

CD95 recruits PLCγ1 to trigger a calcium response promoting Th17 accumulation in inflamed organs of lupus mice
by: Poissonnier, Amanda, et al.
Published: (2016)

Polyadenylation as a target for anti-inflammatory drugs
by: Radhi, Masar
Published: (2019)

Anti-inflammatory activity of roots of Achyranthes aspera
by: S., Vijaya Kumar, et al.
Published: (2009)

Anti-inflammatory activities of Cinnomomum burmanni Bl
by: Khatib, Alfi, et al.
Published: (2005)

Enhanced anti-inflammatory effects of nanoencapsulated diclofenac
by: Goh, Jun Zheng, et al.
Published: (2013)

Anti-inflammatory activity of Jatropha curcas extracts
by: Othman, Ahmad Razi, et al.
Published: (2014)

Honey and its nutritional and anti-inflammatory value
by: Ranneh, Yazan, et al.
Published: (2021)

The Effects of S-Allyl-Cysteine and Cannabidiol on Cerebral and Retinal Neurovascular Integrity and Cognitive Function in Type 2 Diabetes
by: Majimbi, Maimuna
Published: (2024)

Anti-inflammatory and anti-hyperalgesic effects of Ardisia crispa Thunb. D.C
by: Abd Hamid @ Abdul Razak, Roslida, et al.
Published: (2008)

Anti-inflammatory and anti-nociceptive activities of the ethanolic extract of Annona muricata leaf
by: Abd Hamid @ Abdul Razak, Roslida, et al.
Published: (2010)

Anti-inflammatory and anti-hyperalgesic acitivities of Acanthopanax trifoliatus (L.) Merr leaves
by: Abd Hamid @ Abdul Razak, Roslida, et al.
Published: (2013)