Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand

Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand

Objective Osteoarthritis (OA) is the most common form of arthritis and the leading cause of disability in the elderly. Of all the joints, genetic predisposition is strongest for OA of the hand; however, only few genetic risk loci for hand OA have been identified. Our aim was to identify novel genes...

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Main Authors: Hollander, Wouter den, Boer, Cindy G., Hart, Deborah J., Yau, Michelle S., Ramos, Yolande F.M., Metrustry, Sarah, Broer, Linda, Deelen, Joris, Cupples, L. Adrienne, Rivadeneira, Fernando, Kloppenburg, Margreet, Peters, Marjolein, Spector, Tim D., Hofman, Albert, Slagboom, P. Eline, Nelissen, Rob G.H.H., Uitterlinden, André G., Felson, David T., Valdes, Ana M., Meulenbelt, Ingrid, van Meurs, Joyce J.B.
Format: Article
Published: BMJ Publishing Group 2017
Online Access:https://eprints.nottingham.ac.uk/48020/

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