Regulation of human feto-placental endothelial barrier integrity by vascular endothelial growth factors: competitive interplay between VEGF-A165a, VEGF-A165b, PIGF and VE-cadherin
The human placenta nourishes and protects the developing fetus whilst influencing maternal physiology for fetal advantage. It expresses several members of the VEGF family including the pro-angiogenic/pro-permeability VEGF-A165a isoform, the anti-angiogenic VEGF-A165b, placental growth factor (PIGF)...
| Main Authors: | Pang, Vincent, Bates, David O., Leach, Lopa |
|---|---|
| Format: | Article |
| Published: |
Portland Press
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/47699/ |
Similar Items
Diabetic neuropathy: a mechanism of TRPV1 sensitisation and the treatment with Vascular Endothelial Growth Factor-A165b (VEGF-A165b)
by: Bestall, Samuel
Published: (2017)
by: Bestall, Samuel
Published: (2017)
The effect of gestational diabetes on human umbilical mesenchymal stem cells and their ability to influence endothelial permeability
by: Salem, Samar
Published: (2023)
by: Salem, Samar
Published: (2023)
The effect of gestational diabetes, and its treatment, on the expression of Occludin, VE-cadherin & Plakoglobin splice variants in the human placental endothelial barrier
by: Villota Villafuerte, Stephany D.
Published: (2019)
by: Villota Villafuerte, Stephany D.
Published: (2019)
Effects of VEGF-A165b and SRPK1 inhibition on pain behaviour, cyclooxygenase expression and glial activation in the CNS in a model of osteoarthritis
by: Almahasneh, Fatimah
Published: (2018)
by: Almahasneh, Fatimah
Published: (2018)
Effect of hyperglycaemia on VEGF-A splice variants, junctional integrity and vascular leakage in human feto-placental vessels from normal and type 1 diabetic pregnancies
by: Sciota, Flavia
Published: (2012)
by: Sciota, Flavia
Published: (2012)
Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: junctional dynamics and putative mechanisms
by: Ebrahim, Neven A., et al.
Published: (2016)
by: Ebrahim, Neven A., et al.
Published: (2016)
Effects of receptor tyrosine kinase inhibitors on VEGF165a- and VEGF165b-stimulated gene transcription in HEK-293 cells expressing human VEGFR2
by: Carter, Joanne J., et al.
Published: (2015)
by: Carter, Joanne J., et al.
Published: (2015)
Role of VEGF-A in chronic pain
by: Hulse, Richard P.
Published: (2017)
by: Hulse, Richard P.
Published: (2017)
The development of a rapid test for vascular endothelial growth factor (VEGF) detection and the effects of VEGF and anti-VEGF on permeability of endothelial cells
by: Lim, Sheng Jye
Published: (2024)
by: Lim, Sheng Jye
Published: (2024)
Differential regulation of blood flow induced neovascularisation and mural cell recruitment by VEGF and angiopoietin signaling
by: Stone, Oliver A., et al.
Published: (2017)
by: Stone, Oliver A., et al.
Published: (2017)
VEGF-A165b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney
by: Stevens, Megan, et al.
Published: (2017)
by: Stevens, Megan, et al.
Published: (2017)
Temporal studies into attachment, VE-cadherin perturbation, and paracellular migration of human umbilical mesenchymal stem cells across umbilical vein endothelial monolayers
by: Ebrahim, Neven A., et al.
Published: (2015)
by: Ebrahim, Neven A., et al.
Published: (2015)
Probing E-cadherin Targeting Peptides Using Atomic Force Microscopy
by: Studd, Adam
Published: (2022)
by: Studd, Adam
Published: (2022)
Serum vascular endothelial growth
factor (vegf) as a biomarker of lupus
nephritis
by: Iberahim, Rahimah
Published: (2013)
by: Iberahim, Rahimah
Published: (2013)
Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration
by: Hulse, Richard P., et al.
Published: (2015)
by: Hulse, Richard P., et al.
Published: (2015)
The transcriptional regulation of VEGF production from pulmonary artery smooth muscle cells by TGFβ1
by: Clifford, Rachel
Published: (2009)
by: Clifford, Rachel
Published: (2009)
Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina
by: Ved, Nikita, et al.
Published: (2017)
by: Ved, Nikita, et al.
Published: (2017)
Human amniotic membrane as a matrix for endothelial differentiation of VEGF-treated dental stem cells
by: Md Hashim, Siti Nurnasihah, et al.
Published: (2019)
by: Md Hashim, Siti Nurnasihah, et al.
Published: (2019)
Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development
by: Metzler, Veronika M., et al.
Published: (2017)
by: Metzler, Veronika M., et al.
Published: (2017)
Türk-Rus ilişkileri ve FETÖ (Turkish-Russian relations and the FETO)
by: Kayadibi, Saim
Published: (2016)
by: Kayadibi, Saim
Published: (2016)
Real-time ligand binding of fluorescent VEGF-A isoforms that discriminate between VEGFR2 and NRP1 in living cells
by: Peach, Chloe J., et al.
Published: (2018)
by: Peach, Chloe J., et al.
Published: (2018)
Real-time analysis of the binding of fluorescent VEGF₁₆₅a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes
by: Kilpatrick, Laura E., et al.
Published: (2017)
by: Kilpatrick, Laura E., et al.
Published: (2017)
Vascular endothelial growth factor-A165b restores normal glomerular water permeability in a diphtheria-toxin mouse model of glomerular injury
by: Stevens, Megan, et al.
Published: (2018)
by: Stevens, Megan, et al.
Published: (2018)
The influences of dietary protein on bovine placental development and ovarian function
by: Edwards, Jennifer L.
Published: (2017)
by: Edwards, Jennifer L.
Published: (2017)
Involvement of mek signalling on endothelial-like differentiation of dental stem cells cultured on human amniotic membrane with VEGF treatment
by: Yusof, Muhammad Fuad Hilmi
Published: (2021)
by: Yusof, Muhammad Fuad Hilmi
Published: (2021)
Differential regulation of LPS-mediated VE-cadherin disruption in human endothelial cells and the underlying signaling pathways: a mini review
by: Chan, Yee Han, et al.
Published: (2020)
by: Chan, Yee Han, et al.
Published: (2020)
An international network (PlaNet) to evaluate a human placental testing platform for chemicals safety testing in pregnancy
by: Brownbill, Paul, et al.
Published: (2016)
by: Brownbill, Paul, et al.
Published: (2016)
The influence of maternal obesity on placental fatty acid composition, synthesis of inflammatory mediators and pregnancy outcomes
by: Wainwright, Esther
Published: (2024)
by: Wainwright, Esther
Published: (2024)
Purinergic signalling involvement in the regulation of the human placental vasculature
by: Fodor, P.
Published: (2022)
by: Fodor, P.
Published: (2022)
Possible roles for folic acid in the regulation of trophoblast invasion and placental development in normal early human pregnancy
by: Williams, Paula J., et al.
Published: (2011)
by: Williams, Paula J., et al.
Published: (2011)
Expression of vascular endothelial growth factor (VEGF) and its receptor (VEGFR) in thyroid nodular hyperplasia and papillary thyroid carcinoma (PTC)
by: Razy, Nur Hidayati Mohamad Pakarul
Published: (2017)
by: Razy, Nur Hidayati Mohamad Pakarul
Published: (2017)
Placental expression of eNOS, iNOS and the major protein components of caveolae in women with pre-eclampsia
by: Smith-Jackson, Kate, et al.
Published: (2015)
by: Smith-Jackson, Kate, et al.
Published: (2015)
Effect of cord blood cotinine towards placental VEGF expression in pregnant second hand smoker / Muadz Baharom
by: Baharom, Muadz
Published: (2016)
by: Baharom, Muadz
Published: (2016)
Investigation of the contribution of vascular endothelial growth factor and its splicing axis to joint inflammation and damage in arthritis
by: Sohail, Roheena
Published: (2024)
by: Sohail, Roheena
Published: (2024)
The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport
by: Daniel, Zoe, et al.
Published: (2016)
by: Daniel, Zoe, et al.
Published: (2016)
Role of Vascular Endothelial Growth Factor (VEGF) and doppler sub-endometrial parameters as predictors of successful
implantation in Intracytoplasmic Sperm Injection (ICSI) patients
by: Rahmatullah, Wafaa Salih, et al.
Published: (2020)
by: Rahmatullah, Wafaa Salih, et al.
Published: (2020)
Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response
by: Smith, Stuart J., et al.
Published: (2015)
by: Smith, Stuart J., et al.
Published: (2015)
Impaired vasocontractile responses to adenosine in chorionic vessels of human term placenta from pregnant women with pre-existing and gestational diabetes
by: Razak, Azlina A., et al.
Published: (2018)
by: Razak, Azlina A., et al.
Published: (2018)
Comparative study of the biological properties of foetal and placental distal ends of human umbilical cord wharton's jelly mesenchymal stem cells
by: Yusoff, Zuraidah
Published: (2015)
by: Yusoff, Zuraidah
Published: (2015)
A comparison study on aqueous humor transforming growth factor-beta (TGF-β) and vascular endothelial growth factor (VEGF) level in primary glaucoma patients and controls
by: Samsudin, Norhayaty
Published: (2017)
by: Samsudin, Norhayaty
Published: (2017)
Similar Items
-
Diabetic neuropathy: a mechanism of TRPV1 sensitisation and the treatment with Vascular Endothelial Growth Factor-A165b (VEGF-A165b)
by: Bestall, Samuel
Published: (2017) -
The effect of gestational diabetes on human umbilical mesenchymal stem cells and their ability to influence endothelial permeability
by: Salem, Samar
Published: (2023) -
The effect of gestational diabetes, and its treatment, on the expression of Occludin, VE-cadherin & Plakoglobin splice variants in the human placental endothelial barrier
by: Villota Villafuerte, Stephany D.
Published: (2019) -
Effects of VEGF-A165b and SRPK1 inhibition on pain behaviour, cyclooxygenase expression and glial activation in the CNS in a model of osteoarthritis
by: Almahasneh, Fatimah
Published: (2018) -
Effect of hyperglycaemia on VEGF-A splice variants, junctional integrity and vascular leakage in human feto-placental vessels from normal and type 1 diabetic pregnancies
by: Sciota, Flavia
Published: (2012)