Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England

Purpose: The burden of alcohol-attributable disease is a global problem. Young people often present to emergency health-care services with alcohol intoxication but little is known about how best to intervene at that point to improve future health outcomes. This study aimed to assess whether young pe...

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Main Authors: Lester, Louise, Baker, Ruth, Coupland, Carol, Orton, Elizabeth
Format: Article
Published: Elsevier 2018
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Online Access:https://eprints.nottingham.ac.uk/47583/
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author Lester, Louise
Baker, Ruth
Coupland, Carol
Orton, Elizabeth
author_facet Lester, Louise
Baker, Ruth
Coupland, Carol
Orton, Elizabeth
author_sort Lester, Louise
building Nottingham Research Data Repository
collection Online Access
description Purpose: The burden of alcohol-attributable disease is a global problem. Young people often present to emergency health-care services with alcohol intoxication but little is known about how best to intervene at that point to improve future health outcomes. This study aimed to assess whether young people with an alcohol-specific hospital admission are at increased risk of injury following discharge. Methods: A cohort study was conducted using a general population of 10- to 24-year-olds identified using primary care medical records with linked hospital admission records between 1998 and 2013. Exposed individuals had an alcohol-specific admission. Unexposed individuals did not and were frequency matched by age (±5 years) and general practice (ratio 10:1). Incidence rates of injury-related hospital admission post discharge were calculated, and hazard ratios (HR) were estimated by Cox regression. Results: The cohort comprised 11,042 exposed and 110,656 unexposed individuals with 4,944 injury-related admissions during follow-up (2,092 in exposed). Injury rates were six times higher in those with a prior alcohol admission (73.92 per 1,000 person-years, 95% confidence interval (CI) 70.82–77.16 vs. 12.36, 11.91–12.81). The risk of an injury admission was highest in the month following an alcohol-specific admission (adjusted HR = 15.62, 95% CI 14.08–17.34), and remained higher compared to those with no previous alcohol-specific admission at 1 year (HR 5.28 (95% CI 4.97–5.60)) and throughout follow-up. Conclusions: Young people with an alcohol-specific admission are at increased risk of subsequent injury requiring hospitalization, especially immediately post discharge, indicating a need for prompt intervention as soon as alcohol misuse behaviors are identified.
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spelling nottingham-475832020-05-04T19:51:55Z https://eprints.nottingham.ac.uk/47583/ Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England Lester, Louise Baker, Ruth Coupland, Carol Orton, Elizabeth Purpose: The burden of alcohol-attributable disease is a global problem. Young people often present to emergency health-care services with alcohol intoxication but little is known about how best to intervene at that point to improve future health outcomes. This study aimed to assess whether young people with an alcohol-specific hospital admission are at increased risk of injury following discharge. Methods: A cohort study was conducted using a general population of 10- to 24-year-olds identified using primary care medical records with linked hospital admission records between 1998 and 2013. Exposed individuals had an alcohol-specific admission. Unexposed individuals did not and were frequency matched by age (±5 years) and general practice (ratio 10:1). Incidence rates of injury-related hospital admission post discharge were calculated, and hazard ratios (HR) were estimated by Cox regression. Results: The cohort comprised 11,042 exposed and 110,656 unexposed individuals with 4,944 injury-related admissions during follow-up (2,092 in exposed). Injury rates were six times higher in those with a prior alcohol admission (73.92 per 1,000 person-years, 95% confidence interval (CI) 70.82–77.16 vs. 12.36, 11.91–12.81). The risk of an injury admission was highest in the month following an alcohol-specific admission (adjusted HR = 15.62, 95% CI 14.08–17.34), and remained higher compared to those with no previous alcohol-specific admission at 1 year (HR 5.28 (95% CI 4.97–5.60)) and throughout follow-up. Conclusions: Young people with an alcohol-specific admission are at increased risk of subsequent injury requiring hospitalization, especially immediately post discharge, indicating a need for prompt intervention as soon as alcohol misuse behaviors are identified. Elsevier 2018-04 Article PeerReviewed Lester, Louise, Baker, Ruth, Coupland, Carol and Orton, Elizabeth (2018) Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England. Journal of Adolescent Health, 62 (4). pp. 450-456. ISSN 1879-1972 Alcohols Hospitalization Adolescent Risk Wounds and Injuries http://www.sciencedirect.com/science/article/pii/S1054139X17304998?via%3Dihub doi:10.1016/j.jadohealth.2017.10.003 doi:10.1016/j.jadohealth.2017.10.003
spellingShingle Alcohols
Hospitalization
Adolescent
Risk
Wounds and Injuries
Lester, Louise
Baker, Ruth
Coupland, Carol
Orton, Elizabeth
Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England
title Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England
title_full Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England
title_fullStr Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England
title_full_unstemmed Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England
title_short Alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in England
title_sort alcohol misuse and injury outcomes in young people aged 10-24: a cohort analysis using linked primary and secondary care data in england
topic Alcohols
Hospitalization
Adolescent
Risk
Wounds and Injuries
url https://eprints.nottingham.ac.uk/47583/
https://eprints.nottingham.ac.uk/47583/
https://eprints.nottingham.ac.uk/47583/