Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank

UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging compo...

Full description

Bibliographic Details
Main Authors: Alfaro-Almagro, Fidel, Jenkinson, Mark, Bangerter, Neal K., Andersson, Jesper L.R., Griffanti, Ludovica, Douaud, Gwenaëlle, Sotiropoulos, Stamatios N., Jbabdi, Saad, Hernandez-Fernandez, Moises, Vallee, Emmanuel, Vidaurre, Diego, Webster, Matthew, McCarthy, Paul, Rorden, Christopher, Daducci, Alessandro, Alexander, Daniel C., Zhang, Hui, Dragonu, Iulius, Matthews, Paul M., Miller, Karla L., Smith, Stephen M.
Format: Article
Published: Elsevier 2018
Subjects:
Online Access:https://eprints.nottingham.ac.uk/47544/
_version_ 1848797571783327744
author Alfaro-Almagro, Fidel
Jenkinson, Mark
Bangerter, Neal K.
Andersson, Jesper L.R.
Griffanti, Ludovica
Douaud, Gwenaëlle
Sotiropoulos, Stamatios N.
Jbabdi, Saad
Hernandez-Fernandez, Moises
Vallee, Emmanuel
Vidaurre, Diego
Webster, Matthew
McCarthy, Paul
Rorden, Christopher
Daducci, Alessandro
Alexander, Daniel C.
Zhang, Hui
Dragonu, Iulius
Matthews, Paul M.
Miller, Karla L.
Smith, Stephen M.
author_facet Alfaro-Almagro, Fidel
Jenkinson, Mark
Bangerter, Neal K.
Andersson, Jesper L.R.
Griffanti, Ludovica
Douaud, Gwenaëlle
Sotiropoulos, Stamatios N.
Jbabdi, Saad
Hernandez-Fernandez, Moises
Vallee, Emmanuel
Vidaurre, Diego
Webster, Matthew
McCarthy, Paul
Rorden, Christopher
Daducci, Alessandro
Alexander, Daniel C.
Zhang, Hui
Dragonu, Iulius
Matthews, Paul M.
Miller, Karla L.
Smith, Stephen M.
author_sort Alfaro-Almagro, Fidel
building Nottingham Research Data Repository
collection Online Access
description UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted MRI, Resting fMRI, Task fMRI and Diffusion MRI). Raw and processed data from the first 10,000 imaged subjects has recently been released for general research access. To help convert this data into useful summary information we have developed an automated processing and QC (Quality Control) pipeline that is available for use by other researchers. In this paper we describe the pipeline in detail, following a brief overview of UK Biobank brain imaging and the acquisition protocol. We also describe several quantitative investigations carried out as part of the development of both the imaging protocol and the processing pipeline.
first_indexed 2025-11-14T20:06:00Z
format Article
id nottingham-47544
institution University of Nottingham Malaysia Campus
institution_category Local University
last_indexed 2025-11-14T20:06:00Z
publishDate 2018
publisher Elsevier
recordtype eprints
repository_type Digital Repository
spelling nottingham-475442020-05-04T19:29:49Z https://eprints.nottingham.ac.uk/47544/ Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank Alfaro-Almagro, Fidel Jenkinson, Mark Bangerter, Neal K. Andersson, Jesper L.R. Griffanti, Ludovica Douaud, Gwenaëlle Sotiropoulos, Stamatios N. Jbabdi, Saad Hernandez-Fernandez, Moises Vallee, Emmanuel Vidaurre, Diego Webster, Matthew McCarthy, Paul Rorden, Christopher Daducci, Alessandro Alexander, Daniel C. Zhang, Hui Dragonu, Iulius Matthews, Paul M. Miller, Karla L. Smith, Stephen M. UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted MRI, Resting fMRI, Task fMRI and Diffusion MRI). Raw and processed data from the first 10,000 imaged subjects has recently been released for general research access. To help convert this data into useful summary information we have developed an automated processing and QC (Quality Control) pipeline that is available for use by other researchers. In this paper we describe the pipeline in detail, following a brief overview of UK Biobank brain imaging and the acquisition protocol. We also describe several quantitative investigations carried out as part of the development of both the imaging protocol and the processing pipeline. Elsevier 2018-02-01 Article PeerReviewed Alfaro-Almagro, Fidel, Jenkinson, Mark, Bangerter, Neal K., Andersson, Jesper L.R., Griffanti, Ludovica, Douaud, Gwenaëlle, Sotiropoulos, Stamatios N., Jbabdi, Saad, Hernandez-Fernandez, Moises, Vallee, Emmanuel, Vidaurre, Diego, Webster, Matthew, McCarthy, Paul, Rorden, Christopher, Daducci, Alessandro, Alexander, Daniel C., Zhang, Hui, Dragonu, Iulius, Matthews, Paul M., Miller, Karla L. and Smith, Stephen M. (2018) Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank. NeuroImage, 166 . pp. 400-424. ISSN 1095-9572 Epidemiological studies; Image analysis pipeline; Multi-modal data integration; Quality control; Big data imaging; Machine learning http://www.sciencedirect.com/science/article/pii/S1053811917308613 doi:10.1016/j.neuroimage.2017.10.034 doi:10.1016/j.neuroimage.2017.10.034
spellingShingle Epidemiological studies; Image analysis pipeline; Multi-modal data integration; Quality control; Big data imaging; Machine learning
Alfaro-Almagro, Fidel
Jenkinson, Mark
Bangerter, Neal K.
Andersson, Jesper L.R.
Griffanti, Ludovica
Douaud, Gwenaëlle
Sotiropoulos, Stamatios N.
Jbabdi, Saad
Hernandez-Fernandez, Moises
Vallee, Emmanuel
Vidaurre, Diego
Webster, Matthew
McCarthy, Paul
Rorden, Christopher
Daducci, Alessandro
Alexander, Daniel C.
Zhang, Hui
Dragonu, Iulius
Matthews, Paul M.
Miller, Karla L.
Smith, Stephen M.
Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
title Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
title_full Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
title_fullStr Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
title_full_unstemmed Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
title_short Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
title_sort image processing and quality control for the first 10,000 brain imaging datasets from uk biobank
topic Epidemiological studies; Image analysis pipeline; Multi-modal data integration; Quality control; Big data imaging; Machine learning
url https://eprints.nottingham.ac.uk/47544/
https://eprints.nottingham.ac.uk/47544/
https://eprints.nottingham.ac.uk/47544/