Interplay between EZH2 and G9a regulates CXCL10 gene repression in idiopathic pulmonary fibrosis

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Interplay between EZH2 and G9a regulates CXCL10 gene repression in idiopathic pulmonary fibrosis

Selective repression of the antifibrotic gene CXCL10 contributes to tissue remodelling in idiopathic pulmonary fibrosis (IPF). We have previously reported that histone deacetylation and histone H3 lysine 9 (H3K9) methylation are involved in CXCL10 repression. This study explored the role of H3K27 me...

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Bibliographic Details
Main Authors:	Coward, William R., Brand, Oliver J., Pasini, Alice, Jenkins, Gisli, Knox, Alan J., Pang, Linhua
Format:	Article
Published:	American Thoracic Society 2017
Subjects:	histone methylation; CXCL10; gene expression; lung fibroblast; pulmonary fibrosis
Online Access:	https://eprints.nottingham.ac.uk/47494/

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