Recombinant human L-ficolin directly neutralizes hepatitis C virus entry

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Recombinant human L-ficolin directly neutralizes hepatitis C virus entry

L-ficolin is a soluble pattern recognition molecule expressed by the liver that contributes to innate immune defense against microorganisms. It is well described that binding of L-ficolin to specific pathogen-associated molecular patterns activates the lectin complement pathway, resulting in opsoniz...

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Bibliographic Details
Main Authors:	Hamed, Mohamed R., Brown, Richard J.P., Zothner, Carsten, Urbanowicz, Richard A., Mason, Christopher P., Krarup, Anders, McClure, C. Patrick, Irving, William L., Ball, Jonathan K., Harrison, Mark, Hickling, Timothy P., Tarr, Alexander W.
Format:	Article
Published:	Karger 2014
Subjects:	Hepatitis C virus; Ficolin virus entry; Neutralization; Glycosylation
Online Access:	https://eprints.nottingham.ac.uk/47402/

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