Screening for potential embryotoxicity of phytochemicals and gestational diabetes mellitus using the chick cardiomyocyte micromass system and stem cell differentiation: prediction by molecular targets

QR Code

Screening for potential embryotoxicity of phytochemicals and gestational diabetes mellitus using the chick cardiomyocyte micromass system and stem cell differentiation: prediction by molecular targets

Congenital heart defects are a leading cause of postnatal loss; they could genetically or environmentally induced. Herbal remedies are often used during the early stages of pregnancy, being considered ‘harmless’ and ‘natural'. To alleviate pregnancy-induced symptoms, women frequently use herbal...

Full description

Bibliographic Details
Main Author:	Mohammed, Omar Jasim Mohammed
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	Chick embryonic cardiomyocytes Micromass Mouse D3 embryonic stem cells Herbal medicines 6-Gingerol Ginkgolide A Ginkgolide B Ginsenoside Rg1 Bisabolol Eugenol embryotoxicity teratogenicity Diabetes
Online Access:	https://eprints.nottingham.ac.uk/47290/

Similar Items

Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation
by: Dixon, James E., et al.
Published: (2014)

The chick cardiomyocyte micromass system and stem cell differentiation along specific pathways : prediction of embryotoxic effects and their mechanism
by: Shaikh Qureshi, Wasay Mohiuddin
Published: (2012)

Improving the mesodermal differentiation potential of human embryonic stem cells
by: Burridge, Paul Wesley
Published: (2008)

Routing of embryonic arrays using genetic algorithms
by: Ortega-Sanchez, Cesar
Published: (2003)

Embodiment of twenty-first century zeitgeist in Chick Lit
by: Abu Ujum, Diana
Published: (2017)

Untargeted tandem mass spectrometry-based molecular network and zebrafish embryotoxicity and teratogenic effects of Christia vespertilionis (L. F.) Bakh. F. leaf extract
by: Norazhar, Anis Irfan
Published: (2020)

Lead-lag relationships in an embryonic stock market: exploring the role of institutional ownership and liquidity
by: Arjoon, Vaalmikki, et al.
Published: (2016)

Establishment of conditional Wnt5a transgenic embryonic stem cell line and its application during neural differentiation process
by: Mohamed Hisham, Nurul Afiqah
Published: (2017)

Embryonic and early larval development of seven-line barb (Probarbus jullieni sauvage 1880) and lemon fin barb hybrid (Hypsibarbus wetmorei smith 1931 x Barbonymus gonionotus bleeker 1849)
by: Zakaria, Mohd Hazmadi
Published: (2015)

Embryonic, larval development, growth performance and salinity tolerance of Crassostrea belcheri sowerby and Crassostrea iredalei faustino hybrids
by: Wan Nawang, Wan Nur Fatin Syafiqah
Published: (2016)

Current status of drug screening and disease modelling in human pluripotent stem cells
by: Rajamohan, Divya, et al.
Published: (2013)

Defining and manipulating the epigenetic stability of human embryonic stem cells
by: Kim, Kee-Pyo
Published: (2009)

Probing E-cadherin Targeting Peptides Using Atomic Force Microscopy
by: Studd, Adam
Published: (2022)

Generation and Characterisation of Mesenchymal Stem Cells Derived from Placenta and Adult Cardiac Tissue
by: Vellasamy, Shalini
Published: (2011)

Spatiotemporal expression patterns of Pax6 in the brain of embryonic, newborn, and adult mice
by: Duan, D., et al.
Published: (2012)

Building 3D architectures for cardiomyocytes
by: Turgut, Aylin
Published: (2021)

Extraction of eugenol from betel leaves (Piper betle L.) using hydrodistillation and supercritical carbon dioxide technique
by: Nik Hadzir, Noor Hadzuin
Published: (2012)

Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies?
by: Kalra, Spandan, et al.
Published: (2016)

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development
by: Mora-Lorca, José Antonio, et al.
Published: (2016)

Investigating stem cell interactions using Atomic force microscopy
by: Graumuller, Friedrich
Published: (2019)

Modulation of lipidomic markers in oxidative stress neural-derived embryonic stem cell cultures with vitamin E supplementation
by: Abd Jalil, Afifah
Published: (2017)

The effects of undernutrition and dexamethasone treatment on cultured rat neonatal cardiomyocytes
by: Austin, Ruth Marie
Published: (2010)

Investigations into biological factors associated with variation in growth performance of broiler chicks.
by: Elvis-Chikwem, Chinwendu Lorrita
Published: (2025)

Engineered human pluripotent stem cell derived cardiomyocyte platforms to detect cardiovascular safety liabilities
by: Firth, Karl
Published: (2017)

Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
by: Denning, Chris, et al.
Published: (2016)

The effect of hypoxia and reoxygenation on STAT3 regulation in potential cardiomyocyte models
by: Evans, Emma Louise
Published: (2012)

Early epigenetic reprogramming in fertilized, cloned, and parthenogenetic embryos
by: Sepulveda-Rincon, Lessly P., et al.
Published: (2016)

Bio-Inspired Hardware Using FPGAs
by: Ortega-Sanchez, Cesar
Published: (2005)

Evaluating human induced pluripotent stem cell-derived cardiomyocytes for commercial drug testing
by: Katili, Puspita Anggraini
Published: (2020)

DNA methylation analysis of Sox2 regulatory regions SRR1 and SRR2 in undifferentiated and differentiated mouse embryonic stem cells
by: Batool, Sajida
Published: (2013)

Preclinical Evaluation of Andrographis Paniculata (burm.f.) Wall. Ex Ness as Herbal Medicine for Treatment of Breast and Prostate Cancers
by: Yong, Audrey Chee Hu
Published: (2011)

In Vitro Immunomodulatory Effects of Selected Fruits and Herbs on Human Peripheral Blood Mononuclear Cells
by: Chai, Pei Shin
Published: (2010)

MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo
by: Sala, L., et al.
Published: (2017)

Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology
by: Lei, Chon-Lok, et al.
Published: (2017)

A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays
by: Patel, Asha K., et al.
Published: (2015)

Potential Anti-Inflammatory, Anti-pyretic and Anti-Ulcerative Effects of Hexane Fraction of Ardisia Crispa (thumb.) A.DC.
by: Lau, Moi Fong
Published: (2011)

Growth performance and phytochemicals of Vernonia amygdalina Delile as affected by light intensity, growing media, harvest time and storage duration
by: A. Bakar, Nursuhaili
Published: (2019)

Physiological response and phytochemical content of Andrographis paniculata (Burm.) as affected by light and nitrogen
by: Rosli, Khairul Azree
Published: (2013)

Effects of selected herbal extracts on sexual maturity, growth performance and immune response of nile tilapia (Oreochromis niloticus Linnaeus)
by: Kareem, Zana Hama Gharib
Published: (2015)

Design and optimization of nanoemulsion formulation containing Clinacanthus nutans Lindau leaf extract for cosmeceutical application
by: Che Sulaiman, Intan Soraya
Published: (2017)