Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method

This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation....

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Main Authors: Lim, Chang Nong, Koh, Kai Seng, Ren, Yong, Chin, Jit Kai, Shi, Yong, Yan, Yuying
Format: Article
Published: MDPI 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/47169/
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author Lim, Chang Nong
Koh, Kai Seng
Ren, Yong
Chin, Jit Kai
Shi, Yong
Yan, Yuying
author_facet Lim, Chang Nong
Koh, Kai Seng
Ren, Yong
Chin, Jit Kai
Shi, Yong
Yan, Yuying
author_sort Lim, Chang Nong
building Nottingham Research Data Repository
collection Online Access
description This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation. In this paper, two different designs are demonstrated, i.e., droplet fission (single layer) and droplet encapsulation (double layer). In addition, the current fabrication approach reduces the overall production interval with the introduction of a custom-made polydimethylsiloxane (PDMS) aligner. Apart from that, the fabricated device is able to generate daughter droplets with the coefficient of variance (CV) below 5% and double emulsions with CV maintained within 10% without involvement of complex surface wettability modification.
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institution University of Nottingham Malaysia Campus
institution_category Local University
last_indexed 2025-11-14T20:04:33Z
publishDate 2017
publisher MDPI
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spelling nottingham-471692020-05-04T18:35:15Z https://eprints.nottingham.ac.uk/47169/ Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method Lim, Chang Nong Koh, Kai Seng Ren, Yong Chin, Jit Kai Shi, Yong Yan, Yuying This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation. In this paper, two different designs are demonstrated, i.e., droplet fission (single layer) and droplet encapsulation (double layer). In addition, the current fabrication approach reduces the overall production interval with the introduction of a custom-made polydimethylsiloxane (PDMS) aligner. Apart from that, the fabricated device is able to generate daughter droplets with the coefficient of variance (CV) below 5% and double emulsions with CV maintained within 10% without involvement of complex surface wettability modification. MDPI 2017-02-10 Article PeerReviewed Lim, Chang Nong, Koh, Kai Seng, Ren, Yong, Chin, Jit Kai, Shi, Yong and Yan, Yuying (2017) Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method. Micromachines, 8 (2). 49/1-49/17. ISSN 2072-666X droplet manipulation microfabrication encapsulation fission http://www.mdpi.com/2072-666X/8/2/49 doi:10.3390/mi8020049 doi:10.3390/mi8020049
spellingShingle droplet manipulation
microfabrication
encapsulation
fission
Lim, Chang Nong
Koh, Kai Seng
Ren, Yong
Chin, Jit Kai
Shi, Yong
Yan, Yuying
Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method
title Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method
title_full Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method
title_fullStr Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method
title_full_unstemmed Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method
title_short Analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method
title_sort analysis of liquid–liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method
topic droplet manipulation
microfabrication
encapsulation
fission
url https://eprints.nottingham.ac.uk/47169/
https://eprints.nottingham.ac.uk/47169/
https://eprints.nottingham.ac.uk/47169/