Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration

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Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration

The reversibility and strength of the previously established dimerization of the important glycopeptide antibiotic vancomycin in four different aqueous solvents (including a medically-used formulation) have been studied using short-column sedimentation equilibrium in the analytical ultracentrifuge a...

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Bibliographic Details
Main Authors:	Phillips-Jones, Mary K., Lithgo, Ryan, Dinu, Vlad, Gillis, Richard B., Harding, John E., Adams, Gary G., Harding, Stephen E.
Format:	Article
Published:	Nature 2017
Subjects:	Biopolymers in vivo Physical chemistry
Online Access:	https://eprints.nottingham.ac.uk/47166/

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