Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer’s disease

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Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer’s disease

Sporadic early onset Alzheimer’s disease (sEOAD) exhibits the symptoms of late onset Alzheimer’s disease (LOAD) but lacks the familial aspect of the early onset familial form. The genetics of Alzheimer’s disease (AD) identifies APOEε4 to be the greatest risk factor; however, it is a complex disease...

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Bibliographic Details
Main Authors:	Chaudhary, Sultan, Patel, Tulsi, Barber, Imelda S., Guetta-Baranes, Tamar, Brookes, Keeley, Chappell, Sally, Turton, James, Guerreiro, Rita, Bras, Jose, Hernandez, Dena, Singleton, Andrew, Hardy, John, Mann, David, Morgan, Kevin
Format:	Article
Language:	English
Published:	Elsevier 2018
Subjects:	Polygenic risk score (PRS); Sporadic early-onset Alzheimer's disease (sEOAD); Genotyping; NeuroX; NeuroChip
Online Access:	https://eprints.nottingham.ac.uk/46892/

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