Screening exon 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease

Screening exon 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease

Early-onset Alzheimer’s disease (EOAD) can be familial (FAD) or sporadic (sEOAD); both have a disease onset ≤ 65 years of age. 451 sEOAD samples were screened for known causative mutations in exon 16 and 17 of the Amyloid Precursor Protein gene (APP). Four samples were shown to be heterozygous for...

Full description

Bibliographic Details
Main Authors: Barber, Imelda S., García-Cárdenas, Jennyfer M., Sakdapanichkul, Chidchanok, Deacon, Christopher, Zapata Erazo, Gabriela, Guerreiro, Rita, Bras, Jose, Hernandez, Dena, Singleton, Andrew, Guetta-Baranes, Tamar, Braae, Anne, Clement, Naomi, Patel, Tulsi, Brookes, Keeley, Medway, Christopher, Chappell, Sally, Mann, David M., Morgan, Kevin
Format: Article
Published: Elsevier 2016
Subjects:
Alzheimer's disease ; Early-onset ; Sporadic ; Screening ; APP ; rs367709245
Online Access:https://eprints.nottingham.ac.uk/46889/

Similar Items

Similar Items