Interfering with the CCL2–glycosaminoglycan axis as a potential approach to modulate neuroinflammation

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Interfering with the CCL2–glycosaminoglycan axis as a potential approach to modulate neuroinflammation

Multiple Sclerosis, a chronic inflammatory demyelinating disease of the central nervous system, involves an increased expression of monocyte chemotactic protein 1 MCP1-/CCL2. For exerting its chemotactic effects, chemokine binding to glycosaminoglycans (GAGs) is required and therefore this interacti...

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Bibliographic Details
Main Authors:	Gschwandtner, Martha, Piccinini, Anna Maria, Geriza, Tanja, Adage, Tiziana, Kungl, Andreas
Format:	Article
Published:	Elsevier 2016
Subjects:	CCL2 decoy Glycosaminoglycans Anti-inflammatory Multiple sclerosis Experimental autoimmune encephalomyelitis
Online Access:	https://eprints.nottingham.ac.uk/46751/

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