In vitro antitumor effects of AHR ligands aminoflavone (AFP 464) and benzothiazole (5F 203) in human renal carcinoma cells

In vitro antitumor effects of AHR ligands aminoflavone (AFP 464) and benzothiazole (5F 203) in human renal carcinoma cells

We investigated activity and mechanism of action of two AhR ligand antitumor agents, AFP 464 and 5F 203 on human renal cancer cells, specifically examining their effects on cell cycle progression, apoptosis, and migration. TK-10, SN12C, Caki-1, and ACHN human renal cancer cell lines were treated wit...

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Bibliographic Details
Main Authors: Luzzani, Gabriela A., Callero, Mariana A., Kuruppu, Anchala I., Trapani, Valentina, Flumian, Carolina, Todaro, Laura, Bradshaw, Tracey D., Loaiza Perez, Andrea I.
Format: Article
Published: Wiley 2017
Subjects:
AFP 464; 5F 203; AhR; Human renal cancer
Online Access:https://eprints.nottingham.ac.uk/46728/

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