Elucidating the interactions between the adhesive and transcriptioanl functions of beta-catenin in normal and cancerous cells

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Elucidating the interactions between the adhesive and transcriptioanl functions of beta-catenin in normal and cancerous cells

Wnt signalling is involved in a wide range of physiological and pathological processes. The presence of an extracellular Wnt stimulus induces cytoplasmic stabilisation and nuclear translocation of beta-catenin, a protein that also plays an essential role in cadherin-mediated adhesion. Two main hypot...

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Bibliographic Details
Main Authors:	van Leeuwen, Ingeborg M. M., Byrne, Helen M, Jensen, Oliver E., King, John R.
Format:	Article
Published:	Elsevier 2007
Subjects:	Adherens junctions colorectal cancer APC mutation crypt dynamics
Online Access:	https://eprints.nottingham.ac.uk/467/

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